Anti-Prosapip1 LZTS3 Antibody

Product Name

Anti-Prosapip1 LZTS3 Antibody

View all PROSAPIP1 Antibodies

SKU/Catalog Number

A14930

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Prosapip1 LZTS3 Antibody (Catalog # A14930). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Prosapip1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-Prosapip1 LZTS3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A14930)

Host

Rabbit

Contents

Prosapip1 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Prosapip1 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human Prosapip1. The immunogen is located within amino acids 590 - 640 of Prosapip1.

Reactive Species

A14930 is reactive to PROSAPIP1 in Human, Mouse, Rat

Observed Molecular Weight

68 kDa

Calculated molecular weight

71.8 kDa

Background of PROSAPIP1

Prosapip1 is a binding partner of the postsynaptic density (PSD) protein ProSAP2/Shank3, a major scaffolding protein in excitatory brain synapses. Prosapip1 is thought to bind ProSAP2/Shank3 through ProSAP2/Shank3's PDZ domain and link it in turn to the Spine-associated Rap-Gap (SPAR). Prosapip1 shares significant homology with another PSD protein, PSD-Zip70, with both coding for a Fez1 domain that can be found in a total of four related protein, forming a novel family of scaffolding molecules termed ‘Fezzins'. Recent studies show that Prosapip1 can be found in endocrine cells in which it is localized primarily in the hormone-storing compartment of these cells, suggesting that Prosapip1 may have other functions in non-neuronal cells.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A14930 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Prosapip1 antibody can be used for detection of Prosapip1 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

See full target information PROSAPIP1

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