Anti-Protein DEK DEK Antibody

Product Name

Anti-Protein DEK DEK Antibody

View all DEK Antibodies

SKU/Catalog Number

A04410

Size

100ul

Form

Liquid

Description

Boster Bio Anti-Protein DEK DEK Antibody catalog # A04410. Tested in WB,IP applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Protein DEK DEK Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04410)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human KCNE3 protein.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A04410 is reactive to DEK in Human

Applications

A04410 is guaranteed for IP, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

42.674kDa

Background of DEK

Angiogenesis inhibitor. Inhibits migration, proliferation and network formation by endothelial cells as well as angiogenesis. This inhibitory effect is selective to endothelial cells as it does not affect the migration of smooth muscle cells or fibroblasts. Does not affect the proliferation of cancer cells in vitro, but inhibits tumor growth and tumor angiogenesis. Acts in an autocrine manner. Inhibits artery neointimal formation and macrophage infiltration. Exhibits heparin-binding activity.

Kikuno R., DNA Res. 6:197-205(1999).
Bechtel S., BMC Genomics 8:399-399(2007).
Heilig R., Nature 421:601-607(2003).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:1,000
IP: 1:50-1:100

Validation Images & Assay Conditions

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Figure 1. Western blotting validation for Anti-Protein DEK DEK Antibody A04410

Western blot analysis of DEK on A431 cell lysate using anti-DEK antibody at 1/500 dilution.
Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration

Gene/Protein Information For DEK (Source: Uniprot.org, NCBI)

Alternative Names

D6S231EDEK oncogene (DNA binding); DEK oncogene; DEK; protein DEK DEK D6S231E DEK proto-oncogene protein DEK|DEK oncogene (DNA binding)

For more info on DEK, check out the DEK Infographic

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In this infographic, you will see the following information for DEK: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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