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Product Info Summary
| SKU: | A14525 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IF, WB |
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Product info
Product Name
Anti-Protein FAM193B FAM193B Antibody
SKU/Catalog Number
A14525
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Protein FAM193B FAM193B Antibody (Catalog # A14525). Tested in ELISA, WB, IF applications. This antibody reacts with Human.
Storage & Handling
FAM193B antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Protein FAM193B FAM193B Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A14525)
Host
Rabbit
Contents
FAM193B Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
FAM193B antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human FAM193B. The immunogen is located within amino acids 120 - 170 of FAM193B.
Cross-reactivity
At least two isoforms of FAM193B are known to exist; this antibody will detect both isoforms.
Reactive Species
A14525 is reactive to FAM193B in Human
Observed Molecular Weight
68 kDa
Calculated molecular weight
96.5 kDa
Background of FAM193B
FAM193B, also known as IRIZIO, was initially identified as a protein that is upregulated in alveolar rhabdomyosarcoma (ARMS), a type of fast-growing tumor characterized by chromosomal translocations fusing the PAX3 or PAX7 gene with that of FOXO1. It has been suggested that, in addition to the PAX3-FOXO1 gene fusion, disruption of the Rb and p53 pathways is required for full ARMS tumorigenesis. In PAX3-FOXO1-expressing primary mouse fibroblasts that possessed a defective p53 pathway, FAM193B expression enabled the tumorigenic transformation, suggesting that FAM193B may contribute to rhabdomyosarcomagenesis in humans.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A14525 is guaranteed for ELISA, IF, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
FAM193B antibody can be used for detection of FAM193B by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of FAM193B in Jurkat cell lysate with FAM193B antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
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Immunofluorescence of FAM193B in Jurkat cells with FAM193B antibody at 20 μg/mL.
Specific Publications For Anti-Protein FAM193B FAM193B Antibody (A14525)
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