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Product Info Summary
| SKU: | A14525 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IF, WB |
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Product info
Product Name
Anti-Protein FAM193B FAM193B Antibody
SKU/Catalog Number
A14525
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Protein FAM193B FAM193B Antibody (Catalog # A14525). Tested in ELISA, WB, IF applications. This antibody reacts with Human.
Storage & Handling
FAM193B antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Protein FAM193B FAM193B Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A14525)
Host
Rabbit
Contents
FAM193B Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
FAM193B antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human FAM193B. The immunogen is located within amino acids 120 - 170 of FAM193B.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least two isoforms of FAM193B are known to exist; this antibody will detect both isoforms.
Reactive Species
A14525 is reactive to FAM193B in Human
Applications
A14525 is guaranteed for ELISA, IF, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
96.543kDa
Background of FAM193B
FAM193B, also known as IRIZIO, was initially identified as a protein that is upregulated in alveolar rhabdomyosarcoma (ARMS), a type of fast-growing tumor characterized by chromosomal translocations fusing the PAX3 or PAX7 gene with that of FOXO1. It has been suggested that, in addition to the PAX3-FOXO1 gene fusion, disruption of the Rb and p53 pathways is required for full ARMS tumorigenesis. In PAX3-FOXO1-expressing primary mouse fibroblasts that possessed a defective p53 pathway, FAM193B expression enabled the tumorigenic transformation, suggesting that FAM193B may contribute to rhabdomyosarcomagenesis in humans.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
FAM193B antibody can be used for detection of FAM193B by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of FAM193B in Jurkat cell lysate with FAM193B antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
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Immunofluorescence of FAM193B in Jurkat cells with FAM193B antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For FAM193B (Source: Uniprot.org, NCBI)
Gene Name
FAM193B
Full Name
Protein FAM193B
Weight
96.543kDa
Superfamily
FAM193 family
Alternative Names
DKFZp313I142; family with sequence similarity 193, member B; KIAA1931 FAM193B IRIZIO family with sequence similarity 193 member B protein FAM193B
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on FAM193B, check out the FAM193B Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for FAM193B: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Protein FAM193B FAM193B Antibody (A14525)
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No publications found for A14525
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Customer Reviews
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