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Product Info Summary
| SKU: | A10847 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IHC-P, WB |
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Product info
Product Name
Anti-Protocadherin-12 PCDH12 Antibody
View all Protocadherin-12 Antibodies
SKU/Catalog Number
A10847
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Protocadherin-12 PCDH12 Antibody (Catalog # A10847). Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
PCDH12 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Protocadherin-12 PCDH12 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A10847)
Host
Rabbit
Contents
PCDH12 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
PCDH12 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human PCDH12. The immunogen is located within amino acids 30 - 80 of PCDH12.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
This antibody is predicted to not cross-react with PCDH18.
Reactive Species
A10847 is reactive to PCDH12 in Human, Mouse, Rat
Applications
A10847 is guaranteed for ELISA, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
128.995kDa
Background of Protocadherin-12
Protocadherins comprise the largest group within the cadherin family of calcium-dependent cell-cell adhesion molecules. Protocadherin 12 (PCDH12) was initially identified through PCR screening of mouse heart microvascular endothelial cell RNA; further experiments revealed its mRNA to be strongly expressed in highly vascularized organs such as lung and kidney, in addition to glycogen-rich trophoblasts in the placenta. PCDH12-null mice are viable and fertile, but show reduced placental and embryonic sizes when compared to wild-type mice. Further studies showed significant expression changes in 2, 289 genes, including those involved in tissue morphogenesis, angiogenesis, cell-matrix adhesion and migration, immune response and chromatin remodeling.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
PCDH12 antibody can be used for detection of PCDH12 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of PCDH12 in K562 cell lysate with PCDH12 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
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Immunohistochemistry of PCDH12 in rat lung tissue with PCDH12 antibody at 5 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For PCDH12 (Source: Uniprot.org, NCBI)
Gene Name
PCDH12
Full Name
Protocadherin-12
Weight
128.995kDa
Alternative Names
PCDH12; protocadherin 12; Protocadherin12; Protocadherin-12; Vascular cadherin-2; vascular endothelial cadherin 2; Vascular endothelial cadherin-2; VECAD2; VE-cad-2; VE-cadherin 2; VE-cadherin-2; VE-cadherin-2protocadherin-12 PCDH12 DMJDS1, VE-cadherin-2, VECAD2 protocadherin 12 protocadherin-12|VE-cad-2|VE-cadherin 2|vascular cadherin-2|vascular endothelial cadherin 2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PCDH12, check out the PCDH12 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PCDH12: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Protocadherin-12 PCDH12 Antibody (A10847)
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No publications found for A10847
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