Anti-PSMB10 Antibody

Product Name

Anti-PSMB10 Antibody

View all PSMB10/MECL1 Antibodies

SKU/Catalog Number

A04960

Size

100ul

Form

Liquid

Description

Boster Bio Anti-PSMB10 Antibody catalog # A04960. Tested in WB,IHC,ICC/IF applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-PSMB10 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04960)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human RIN1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A04960 is reactive to PSMB10 in Human, Mouse, Rat

Applications

A04960 is guaranteed for IF, IHC, ICC, WB Boster Guarantee

Observed Molecular Weight

111 kDa

Calculated molecular weight

28.936kDa

Background of PSMB10/MECL1

Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis.

Colicelli J., Proc. Natl. Acad. Sci. U.S.A. 88:2913-2917(1991).
Han L., Mol. Cell. Biol. 15:1318-1323(1995).
Han L., Proc. Natl. Acad. Sci. U.S.A. 94:4954-4959(1997)

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:2000
IHC: 1:50-1:200
ICC/IF: 1:50-1:100

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

Gene/Protein Information For PSMB10 (Source: Uniprot.org, NCBI)

Alternative Names

beta2i; FLJ00366; LMP10; LMP10Proteasome subunit beta-2i; Low molecular mass protein 10; Macropain subunit MECl-1; MECL1; MECl-1; MECL1EC 3.4.25.1; MGC1665; Multicatalytic endopeptidase complex subunit MECl-1; proteasome (prosome, macropain) subunit, beta type, 10; proteasome catalytic subunit 2i; Proteasome MECl-1; proteasome subunit beta 7i; proteasome subunit beta type-10; Proteasome subunit beta-2i; proteasome subunit MECL1; PSMB10 PSMB10 LMP10, MECL1, PRAAS5, beta2i proteasome 20S subunit beta 10 proteasome subunit beta type-10|low molecular mass protein 10|macropain subunit MECl-1|multicatalytic endopeptidase complex subunit MECl-1|proteasome (prosome, macropain) subunit, beta type, 10|proteasome MECl-1|proteasome catalytic subunit 2i|proteasome subunit MECL1|proteasome subunit beta 10|proteasome subunit beta 7i|proteasome subunit beta-2i|proteasome subunit beta2i

For more info on PSMB10, check out the PSMB10 Infographic

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In this infographic, you will see the following information for PSMB10: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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