Anti-PTPN22 Antibody Picoband™

Lyp/PTPN22 antibody

Boster Bio Anti-PTPN22 Antibody Picoband™ catalog # A00581-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A00581-1
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: ELISA, IHC, WB

Product Name

Anti-PTPN22 Antibody Picoband™

View all Lyp/PTPN22 Antibodies

SKU/Catalog Number

A00581-1

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-PTPN22 Antibody Picoband™ catalog # A00581-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-PTPN22 Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00581-1)

Host

Rabbit

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E. coli-derived mouse PTPN22 recombinant protein (Position: M1-Q309).

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

A00581-1 is reactive to Ptpn22 in Human, Mouse, Rat

Applications

A00581-1 is guaranteed for ELISA, IHC, WB Boster Guarantee

Observed Molecular Weight

92 kDa

Calculated molecular weight

89.714kDa

Background of Lyp/PTPN22

Protein tyrosine phosphatase, non-receptor type 22 (lymphoid), also known as PTPN22, is a protein that in humans is encoded by the PTPN22 gene. This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml
Direct ELISA, 0.1-0.5μg/ml

Validation Images & Assay Conditions

Gene/Protein Information For Ptpn22 (Source: Uniprot.org, NCBI)

Gene Name

Ptpn22

Full Name

Tyrosine-protein phosphatase non-receptor type 22

Weight

89.714kDa

Superfamily

protein-tyrosine phosphatase family

Alternative Names

EC 3.1.3.48; Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP; Lymphoid phosphatase; lymphoid-specific protein tyrosine phosphatase; Lyp; Lyp1; Lyp2; LyPTP; PEP; PEST-domain phosphatase; protein tyrosine phosphatase, non-receptor type 22 (lymphoid); protein tyrosine phosphatase, non-receptor type 8; PTPN22; PTPN8 (former); PTPN8LYP1; tyrosine-protein phosphatase non-receptor type 22 Ptpn22|70zp, 70zpep, PEP, Pt, Ptpn8|protein tyrosine phosphatase, non-receptor type 22 (lymphoid)|tyrosine-protein phosphatase non-receptor type 22|PEST domain-enriched tyrosine phosphatase|hematopoietic cell protein-tyrosine phosphatase 70Z-PEP|protein tyrosine phosphatase, non-receptor type 8

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on Ptpn22, check out the Ptpn22 Infographic

Ptpn22 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for Ptpn22: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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4 Customer Q&As for Anti-PTPN22 Antibody Picoband™

Question

We are currently using anti-PTPN22 antibody A00581-1 for mouse tissue, and we are satisfied with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it true that the antibody can work on dog tissues as well?

Verified Customer

Verified customer

Asked: 2020-03-05

Answer

The anti-PTPN22 antibody (A00581-1) has not been tested for cross reactivity specifically with dog tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in dog you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2020-03-05

Question

Does A00581-1 antibody reacts with human PTPN22? Is it specific for mouse PTPN22 only or does it react with other kinases as well?

Verified customer

Asked: 2019-10-11

Answer

Yes, our Anti-PTPN22 Antibody Picoband A00581-1 reacts with human PTPN22. Our lab has not experimentally validated the cross reactivity with other kinases since the sequence homology with other kinase is not very high.

Boster Scientific Support

Answered: 2019-10-15

Question

Is there a BSA free version of anti-PTPN22 antibody A00581-1 available?

Verified Customer

Verified customer

Asked: 2018-09-28

Answer

We appreciate your recent telephone inquiry. I can confirm that some lots of this anti-PTPN22 antibody A00581-1 are BSA free. For now, these lots are available and we can make a BSA free formula for you free of charge. It will take 3 extra days to prepare. If you require this antibody BSA free again in future, please do not hesitate to contact me and I will be pleased to check which lots we have in stock that are BSA free.

Boster Scientific Support

Answered: 2018-09-28

Question

See attached the WB image, lot number and protocol we used for lymph using anti-PTPN22 antibody A00581-1. Please let me know if you require anything else.

Verified Customer

Verified customer

Asked: 2017-08-01

Answer

Thank you very much for the data. Our lab team are working to resolve this as quickly as possible, and we appreciate your patience and understanding! You have provided everything we needed. Please let me know if there is anything you need in the meantime.

Boster Scientific Support

Answered: 2017-08-01

Order DetailsPrice
A00581-1

100μg

$370
A00581-1-10ug

10μg sample (liquid)

$99
A00581-1-Biotin

100 μg Biotin conjugated

$570
A00581-1-Cy3

100 μg Cy3 conjugated

$570
A00581-1-Dylight488

100 μg Dylight488 conjugated

$570
A00581-1-Dylight550

100 μg Dylight550 conjugated

$570
A00581-1-Dylight594

100 μg Dylight594 conjugated

$570
A00581-1-FITC

100 μg FITC conjugated

$570
A00581-1-HRP

100 μg HRP conjugated

$570
A00581-1-APC

100 μg APC conjugated

$670
A00581-1-PE

100 μg PE conjugated

$670
A00581-1-carrier-free

Carrier Free

$370

More conjugates/formats

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A00581-1
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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