Anti-PTPN23 Antibody

Product Name

Anti-PTPN23 Antibody

View all PTPN23 Antibodies

SKU/Catalog Number

A05909

Size

100ul

Form

Liquid

Description

Boster Bio Anti-PTPN23 Antibody catalog # A05909. Tested in WB,IHC applications. This antibody reacts with Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-PTPN23 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05909)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human CRIS3 protein.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A05909 is reactive to PTPN23 in Mouse, Rat

Applications

A05909 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

178.974kDa

Background of PTPN23

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Required for the integrity and for normal function of the Golgi apparatus and the trans-Golgi network. Plays a role in insulin-stimulated translocation of GLUT4 to the cell membrane. Plays a role in M6PR transport from the trans-Golgi network to endosomes. Plays a role in the internalization of EGFR from the cell membrane into endosomes. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.

Chen D., Gene 174:129-134(1996) [PubMed: 8863739].
Bao X.,Eur. J. Biochem. 269:259-271(2002) [PubMed: 11784320].
Ota T., Nat. Genet. 36:40-45(2004) [PubMed: 14702039].<

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:2000
IHC: 1:50-1:200

Validation Images & Assay Conditions

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Figure 1. Western blotting validation for Anti-PTPN23 Antibody A05909

Western blot analysis of extracts of various cells

Gene/Protein Information For PTPN23 (Source: Uniprot.org, NCBI)

Alternative Names

EC 3.1.3.48; HDPTP; HD-PTPDKFZp564F0923; His domain-containing protein tyrosine phosphatase; His-domain protein tyrosine phosphatase; KIAA1471DKFZP564F0923; Protein tyrosine phosphatase TD14; protein tyrosine phosphatase, non-receptor type 23; PTP-TD14; tyrosine-protein phosphatase non-receptor type 23 PTPN23 HD-PTP, HDPTP, NEDBASS, PTP-TD14 protein tyrosine phosphatase non-receptor type 23 tyrosine-protein phosphatase non-receptor type 23|his domain-containing protein tyrosine phosphatase|protein tyrosine phosphatase TD14

For more info on PTPN23, check out the PTPN23 Infographic

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In this infographic, you will see the following information for PTPN23: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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