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Product Info Summary
| SKU: | A01004 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | IHC |
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Product info
Product Name
Anti-RAGE (Q286) MOK Antibody
SKU/Catalog Number
A01004
Size
100ul
Form
Liquid
Description
Boster Bio Anti-RAGE (Q286) MOK Antibody catalog # A01004. Tested in IHC applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-RAGE (Q286) MOK Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01004)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human NUDC around the phosphorylation site of S326.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A01004 is reactive to MOK in Human, Mouse, Rat
Applications
A01004 is guaranteed for IHC Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
48.014kDa
Background of MOK
4E-BP1 encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
Gingras AC, et al. (1998) Genes Dev 12(4): 502-513.
Brugarolas J, et al. (2004) Genes Dev 18(23): 2893-2904.
Kumar V, et al. (2000) EMBO J 19(5): 1087-1097.
Moody CA, et al. (2005) J Virol 79(9): 5499-5506.
Burnett PE, et al. (1998) Proc Natl Acad Sci U S A 95(4): 1432-1437.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IHC: 1:50-1:200
Validation Images & Assay Conditions
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Figure 1. Immunohistochemistry validation of MOK using Anti-RAGE (Q286) MOK Antibody (A01004).
Immunohistochemistry (IHC) analyzes of RAGE (Q286) pAb in paraffin-embedded human tonsil cancer tissue at 1:50.For more protocol information of IHC
Protein Target Info & Infographic
Gene/Protein Information For MOK (Source: Uniprot.org, NCBI)
Gene Name
MOK
Full Name
MAPK/MAK/MRK overlapping kinase
Weight
48.014kDa
Superfamily
protein kinase superfamily
Alternative Names
EC 2.7.11.22; MOK Protein Kinase; MOK; RAGE-1; Renal tumor antigen 1; renal tumor antigen MOK RAGE, RAGE-1, RAGE1, STK30 MOK protein kinase MAPK/MAK/MRK overlapping kinase|renal cell carcinoma antigen|renal tumor antigen 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on MOK, check out the MOK Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for MOK: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-RAGE (Q286) MOK Antibody (A01004)
Hello CJ!
A01004 has been cited in 3 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
Proteomic alteration in lung tissue of rats exposed to cigarette smoke
Involvement of S100A4/Mts1 and associated proteins in the protective effect of fluoxetine against MCT – Induced pulmonary hypertension in rats
Lead Exposure in Developmental Ages Promotes Aβ Accumulation by Disturbing Aβ Transportation in Blood-Cerebrospinal Fluid Barrier/Blood–Brain Barriers and Impairing Aβ Clearance in the Liver
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Customer Reviews
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