MOK Antibodies

AND MOK ELISA kits, MOK Proteins

Many biological assays use antibodies to detect MOK, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MOK in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MOK antibodies...

We validate the specificity of these antibodies to MOK by testing them on tissues known to express MOK positively and negatively. Browse below to find the MOK antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for MOK? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the MOK Western Blot Guide

MOK Infographic by Boster Bio

All MOK Products

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Figures

Specificity

Applications

Price

Anti-MOK Antibody Picoband®

Western blot analysis of MOK using anti-MOK antibody (A01004-4)

Flow Cytometry analysis of A431 cells using anti-MOK antibody (A01004-4)

Human

ELISA, Flow Cytometry, WB

$370
Cat # A01004-4
100 μg/vial

MOK protein kinase (MOK) (NM_014226) Human Over-expression Lysate

Human

$960
Cat # LS005891
20 µg, 100 µg

MOK Overview

Facts about MAPK/MAK/MRK overlapping kinase.

MOK 3D structure. Source: alphafold

MAPK/MAK/MRK overlapping kinase (MOK)

Willing to phosphorylate several exogenous substrates and to undergo autophosphorylation. Negatively regulates cilium span in a cAMP and mTORC1 signaling-dependent method.

Gene Information

Human
Gene Name:	MOK
Uniprot:	Q9UQ07
Entrez:	5891

Family

Belongs to:

protein kinase superfamily

Alternative Names

EC 2.7.11.22; MOK Protein Kinase; MOK; RAGE-1; Renal tumor antigen 1; renal tumor antigen

Molecular Weight

Mass (kDA):
48.014 kDA

Genomic Context


Human

Location:	14q32.31
Sequence:	14; NC_000014.9 (102224441..102305191, complement)

Tissue Specificity

Expressed in heart, brain, lung, kidney, and pancreas, and at very low levels in placenta, liver and skeletal muscle. Detected in retina.

Subcellular Localizations

Cytoplasm. Cell projection, cilium. Nucleus.

Diseases

Neoplasms
Carcinoma
Malignant Neoplasms
Renal Cell Carcinoma
Inflammation
Diabetes Mellitus
Kidney Neoplasm
Neoplasm Metastasis
Atherosclerosis
Alzheimer's Disease
Malignant Paraganglionic Neoplasm
Diabetes Mellitus, Non-insulin-dependent
Autoimmune Reaction

Oncocytic Neoplasm
Conventional (clear Cell) Renal Cell Carcinoma
Multiple Acyl Coenzyme A Dehydrogenase Deficiency
Systemic Infection
Lupus Erythematosus, Systemic
Innate Immune Response
Rabies (disorder)

Pathways

Pathogenesis
Cell Death
Immune Response
Translation
Cell Proliferation
Glycosylation
Aging
Innate Immune Response
Translational Initiation
Secretion
Cell Activation
Hypersensitivity
Localization

Kidney Development
Chemokine Production
Quorum Sensing
T Cell Activation
Lung Development
Leukocyte Activation
Cell Division

PTMs

Phosphorylation
Glycosylation
Oxidation
Methylation

Carboxylation
Cleavage
Deglycosylation
Iodination

Research Areas

Neurodegeneration
Neuronal Cell Markers
Neuroscience
Protein Kinase
Vision

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MOK

References

PMID: 10421840 by Miyata Y., et al. Molecular cloning and characterization of a novel member of the MAP kinase superfamily.

PMID: 8781117 by Gaugler B., et al. A new gene coding for an antigen recognized by autologous cytolytic T lymphocytes on a human renal carcinoma.