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Product Info Summary
| SKU: | A03561-1 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | ELISA, IHC, WB |
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Product info
Product Name
Anti-Rap1GAP Antibody
SKU/Catalog Number
A03561-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Rap1GAP Antibody catalog # A03561-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Rap1GAP Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03561-1)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human Rap1GAP
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A03561-1 is reactive to RAP1GAP in Human, Mouse
Applications
A03561-1 is guaranteed for ELISA, IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
73.361kDa
Background of RAP1GAP
Component of the spliceosome A complex. Regulates alternative splicing of a number of mRNAs. May modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. May both positively and negatively regulate aopotosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis.
Bader S., Submitted (APR-1996) to the EMBL/GenBank/DDBJ databases.
Timmer T., Genomics 60:238-240(1999).
Oh J.J., Nucleic Acids Res. 27:4008-4017(1999).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000
Validation Images & Assay Conditions
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Figure 1. Western blotting validation for Anti-Rap1GAP Antibody A03561-1
Western Blot (WB) analysis of specific cells using Rap1GAP polyclonal antibody.Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
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Figure 2. Western blotting validation for Anti-Rap1GAP Antibody A03561-1
Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For RAP1GAP (Source: Uniprot.org, NCBI)
Gene Name
RAP1GAP
Full Name
Rap1 GTPase-activating protein 1
Weight
73.361kDa
Alternative Names
GTPase activating protein 1; RAP1 GTPase activating protein RAP1GAP RAP1GA11, RAP1GAPII, RAPGAP, RAP1GAP RAP1 GTPase activating protein rap1 GTPase-activating protein 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on RAP1GAP, check out the RAP1GAP Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for RAP1GAP: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Rap1GAP Antibody (A03561-1)
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No publications found for A03561-1
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Customer Reviews
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