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Product Info Summary
| SKU: | A09636 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-Rhomboid-related protein 4 RHBDD1 Antibody
SKU/Catalog Number
A09636
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Rhomboid-related protein 4 RHBDD1 Antibody (Catalog # A09636). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.
Storage & Handling
RHBDD1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Rhomboid-related protein 4 RHBDD1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09636)
Host
Rabbit
Contents
RHBDD1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
RHBDD1 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human RHBDD1. The immunogen is located within the last 50 amino acids of RHBDD1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
VEZT antibody is human, mouse and rat reactive. Multiple isoforms are known to exist.
Reactive Species
A09636 is reactive to Rhbdd1 in Human, Mouse
Applications
A09636 is guaranteed for ELISA, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
35.776kDa
Background of Rhbdd1
The Rhomboid family of proteins is made up of several widely conserved polytopic membrane serine proteases that play roles in growth and development. RHBDD1 is highly expressed in the testis and is involved in the cleavage of BIK, a proapoptotic member of the Bcl-2 family. Overexpression or suppression by RNAi of RHBDD1 in 293 cells will reduce or enhance BIK-mediated apoptosis, respectively, demonstrating that RHBDD1 modulates BIK-mediated apoptotic activity. In GC-1 cells, a spermatogonia cell line that can differentiate into spermatids within the seminiferous tubules, suppression of RHBDD1 expression by RNAi caused the cells to lose the ability to survive and differentiate in mouse seminiferous tubules, suggesting that RHBDD1 may be associated with mammalian spermatogenesis.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
RHBDD1 antibody can be used for detection of RHBDD1 by Western blot at 1 μg/mL.
Antibody validated: Western Blot in human and mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Protein Target Info & Infographic
Gene/Protein Information For Rhbdd1 (Source: Uniprot.org, NCBI)
Gene Name
Rhbdd1
Full Name
Rhomboid-related protein 4
Weight
35.776kDa
Superfamily
peptidase S54 family
Alternative Names
DKFZp547E052; EC 3.4.21; EC 3.4.21.-; MGC117258; rhomboid domain containing 1; rhomboid domain-containing protein 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Rhbdd1, check out the Rhbdd1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Rhbdd1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Rhomboid-related protein 4 RHBDD1 Antibody (A09636)
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No publications found for A09636
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