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Product Info Summary
| SKU: | A09281 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-Rkhd2 MEX3C Antibody
SKU/Catalog Number
A09281
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Rkhd2 MEX3C Antibody (Catalog # A09281). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Rkhd2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Rkhd2 MEX3C Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09281)
Host
Rabbit
Contents
Rkhd2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Rkhd2 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human RKHD2. The immunogen is located within amino acids 540 - 590 of Rkhd2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least three isoforms of MS4A6A are known to exist; this antibody will detect the two longer isoforms. MS4A6A antibody is predicted to not cross-react with MS4A family members.
Reactive Species
A09281 is reactive to MEX3C in Human, Mouse, Rat
Applications
A09281 is guaranteed for ELISA, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
69.366kDa
Background of MEX3C
Rkhd2, also known as MEX3C is a member of a novel family of four homologous human MEX3 proteins each containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module. MEX3 proteins, including Rkhd2, are phosphoproteins that bind RNA through their KH domains and shuttle between the nucleus and the cytoplasm via the CRM1 export pathway. These proteins are a novel family of evolutionarily conserved RNA-binding proteins, differentially recruited to P bodies and potentially involved in post-transcriptional regulatory mechanisms. It has been suggested that genetic variations in Rkhd2 may be associated with susceptibility to essential hypertension type 8. Rkhd3 and Rkhd4, but not Rkhd2, co-localize with both the hDcp1a decapping factor and Argonaute (Ago) proteins in processing bodies (P bodies), recently characterized as centers of mRNA turnover.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Rkhd2 antibody can be used for detection of Rkhd2 by Western blot at 0.5 - 1 μg/mL.
Antibody validated: Western Blot in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of Rkhd2 in rat heart tissue lysate with Rkhd2 antibody at (A) 0.5 μg/mL and (B) 1 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For MEX3C (Source: Uniprot.org, NCBI)
Gene Name
MEX3C
Full Name
RNA-binding E3 ubiquitin-protein ligase MEX3C
Weight
69.366kDa
Alternative Names
BM-013; FLJ38871; mex-3 homolog C (C. elegans); ring finger and KH domain containing 2; RING finger protein 194; RNA-binding protein MEX3C; RNF194 MEX3C BM-013, MEX-3C, RKHD2, RNF194 mex-3 RNA binding family member C RNA-binding E3 ubiquitin-protein ligase MEX3C|MEX3C variant 1|MEX3C variant 2|RING finger and KH domain-containing protein 2|RING finger protein 194|RING-type E3 ubiquitin transferase MEX3C|RNA-binding protein MEX3C|ring finger and KH domain containing 2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on MEX3C, check out the MEX3C Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for MEX3C: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Rkhd2 MEX3C Antibody (A09281)
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No publications found for A09281
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