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- Table of Contents
RC3H1 antibody (A06498) performs well in ELISA, IF, IHC-P, WB and shows reactivity with Human, Mouse, Rat.
- Validated for inter-lot consistency, specificity, and reproducibility
- Committed to quality since 1993
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Immunofluorescence of RC3H1 in human small intestine tissue with RC3H1 antibody at 20 μg/ml.
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Anti-Roquin-1 RC3H1 Antibody
RC3H1 antibody
| Reactive Species | Host | Application |
|---|---|---|
| Human, Mouse, Rat | Rabbit | ELISA, IF, IHC-P, WB |
Recommend Dilution
Application
Dilution
Species
RC3H1 antibody can be used for detection of RC3H1 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
* It is recommended to optimize the amount of this reagent in each experimental system to achieve the best results.
Product Information
Product Name
Anti-Roquin-1 RC3H1 Antibody
View all RC3H1 Antibodies
View all RC3H1 Antibodies
Form
Liquid
Uniprot
Gene ID
Storage & Handling
RC3H1 antibody can be stored at 4°C, stable for up to one year.
Host
Rabbit
Contents
RC3H1 Antibody is supplied in PBS containing ≤0.09% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Rabbit polyclonal RC3H1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human RC3H1. The immunogen is located within amino acids 1040 - 1090 of RC3H1.
Cross-Reactivity
At least three isoforms of RC3H1 are known to exist; this antibody will detect all three isoforms.
Observed Molecular Weight
68 kDa
Calculated Molecular Weight
125.7 kDa
Background of RC3H1
The ring finger protein RC3H1, also known as Roquin, is a highly conserved member of the RING type ubiquitin ligase protein family whose M199R mutation leads to the excessive production of follicular helper T cells and germinal centers in the sanroque strain of mice, a strain with excessive IL-21 production and high titers of autoantibodies. The complete loss of RC3H1 induces early death and immune deregulation but not autoimmunity in RC3H1-null mice, suggesting that the mutant RC3H1 is more disruptive to the immune system than its complete loss.
Cite This Product
Anti-Roquin-1 RC3H1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06498)
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Product Promise
We promise Anti-Roquin-1 RC3H1 Antibody performs excellently in relevant applications for ELISA, IF, IHC-P, WB. If it doesn't perform as promised, we will refund the product. Learn more
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A06498
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$481.00
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We promise all of our products perform as described in datasheets.
This product is for Research Use Only. Not for use in diagnostic procedures.
Update date:
Oct 6, 2026