Anti-SF3B14 SF3B6 Antibody

Product Name

Anti-SF3B14 SF3B6 Antibody

View all SF3B6 Antibodies

SKU/Catalog Number

A10990

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-SF3B14 SF3B6 Antibody (Catalog # A10990). Tested in WB applications. This antibody reacts with Human, Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-SF3B14 SF3B6 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A10990)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from C-terminal of human SF3B14.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A10990 is reactive to SF3B6 in Human, Mouse

Applications

A10990 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

14.585kDa

Background of SF3B6

Necessary for the splicing of pre-mRNA. Directly contacts the pre-mRNA branch site adenosine for the first catalytic step of splicing. Enters the spliceosome and associates with the pre-mRNA branch site as part of the 17S U2 or, in the case of the minor spliceosome, as part of the 18S U11/U12 snRNP complex, and thus may facilitate the interaction of these snRNP with the branch sites of U2 and U12 respectively.

Will C.L., EMBO J. 20:4536-4546(2001).
Lai C.-H., Genome Res. 10:703-713(2000).
Zhang Q.-H., Genome Res. 10:1546-1560(2000).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blotting: 1:500~1:3000

Validation Images & Assay Conditions

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Western blot analysis of extracts from HepG2 cells, using SF3B14 antibody A10990.

Gene/Protein Information For SF3B6 (Source: Uniprot.org, NCBI)

Alternative Names

Splicing factor 3B subunit 6 SF3B6 CGI-110, HSPC175, Ht006, P14, SAP14, SAP14a, SF3B14, SF3B14a splicing factor 3b subunit 6 splicing factor 3B subunit 6|SF3b 14 kDa subunit|pre-mRNA branch site protein p14|spliceosome-associated protein, 14 kDa subunit|spliceosome-associated protein, 14-kDa|splicing factor 3B, 14 kDa subunit|splicing factor 3b, subunit 6, 14kDa

For more info on SF3B6, check out the SF3B6 Infographic

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In this infographic, you will see the following information for SF3B6: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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