Anti-SHP1/PTPN6 Antibody Picoband™

SHP-1 antibody

Boster Bio Anti-SHP1/PTPN6 Antibody Picoband™ catalog # A00938-3. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse.

Product Info Summary

SKU: A00938-3
Size: 100 μg/vial
Reactive Species: Human, Mouse
Host: Rabbit
Application: ELISA, Flow Cytometry, IF, ICC, WB

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Product Name

Anti-SHP1/PTPN6 Antibody Picoband™

View all SHP-1 Antibodies

SKU/Catalog Number

A00938-3

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-SHP1/PTPN6 Antibody Picoband™ catalog # A00938-3. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-SHP1/PTPN6 Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00938-3)

Host

Rabbit

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.01mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E.coli-derived human SHP1/PTPN6 recombinant protein (Position: E67-K572).

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

A00938-3 is reactive to PTPN6 in Human, Mouse

Applications

A00938-3 is guaranteed for ELISA, Flow Cytometry, IF, ICC, WB Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

67.561kDa

Background of SHP-1

Tyrosine-protein phosphatase non-receptor type 6, also known as Src homology region 2 domain-containing phosphatase-1 (SHP-1), is an enzyme that in humans is encoded by the PTPN6 gene. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.25-0.5μg/ml, Human, Mouse
Immunocytochemistry/Immunofluorescence, 5μg/ml, Human
Flow Cytometry, 1-3μg/1x106 cells, Human
Direct ELISA, 0.1-0.5μg/ml, Human

Validation Images & Assay Conditions

Gene/Protein Information For PTPN6 (Source: Uniprot.org, NCBI)

Gene Name

PTPN6

Full Name

Tyrosine-protein phosphatase non-receptor type 6

Weight

67.561kDa

Superfamily

protein-tyrosine phosphatase family

Alternative Names

HCP; HCPH; HPTP1C; PTP1C; PTP-1C; PTPN6; SHP1; SHP-1; SHP-1L; SH-PTP1 PTPN6 HCP, HCPH, HPTP1C, PTP-1C, SH-PTP1, SHP-1, SHP-1L, SHP1 protein tyrosine phosphatase non-receptor type 6 tyrosine-protein phosphatase non-receptor type 6|hematopoietic cell phosphatase|hematopoietic cell protein-tyrosine phosphatase|protein-tyrosine phosphatase 1C|protein-tyrosine phosphatase SHP-1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on PTPN6, check out the PTPN6 Infographic

PTPN6 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for PTPN6: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A00938-3

100μg

$370
A00938-3-10ug

10μg sample (liquid)

$99
A00938-3-Biotin

100 μg Biotin conjugated

$570
A00938-3-Cy3

100 μg Cy3 conjugated

$570
A00938-3-Dylight488

100 μg Dylight488 conjugated

$570
A00938-3-Dylight550

100 μg Dylight550 conjugated

$570
A00938-3-Dylight594

100 μg Dylight594 conjugated

$570
A00938-3-FITC

100 μg FITC conjugated

$570
A00938-3-HRP

100 μg HRP conjugated

$570
A00938-3-APC

100 μg APC conjugated

$670
A00938-3-PE

100 μg PE conjugated

$670
A00938-3-carrier-free

Carrier Free

$370

More conjugates/formats

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A00938-3
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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