Click image to see more details
Product Info Summary
| SKU: | A06424-1 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | IF, WB |
Customers Who Bought This Also Bought
Product info
Product Name
Anti-SIN3B Antibody
SKU/Catalog Number
A06424-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-SIN3B Antibody catalog # A06424-1. Tested in WB,IF applications. This antibody reacts with Human,Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-SIN3B Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06424-1)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from internal of human SIN3B.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A06424-1 is reactive to Sin3b in Human, Mouse
Applications
A06424-1 is guaranteed for IF, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
126.405kDa
Background of Sin3b
Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription By similarity.
Ishikawa K., DNA Res. 5:169-176(1998).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Wysocka J., Genes Dev. 17:896-911(2003).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Innovating Scientists Reward
If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.
Submit A Review
Assay dilution & Images
Reconsitution
Restore with deionized water (or equivalent) for reconstitution volume of 100 µL
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:1000
IF: 1:50-1:200
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Western blotting validation for Anti-SIN3B Antibody A06424-1
Western blot (WB) analysis of SIN3B polyclonal antibody at 1:500 dilutionLane1:Hela cell lysate
Lane2:sp2/0 cell lysate
Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For Sin3b (Source: Uniprot.org, NCBI)
Gene Name
Sin3b
Full Name
Paired amphipathic helix protein Sin3b
Weight
126.405kDa
Alternative Names
Histone deacetylase complex subunit Sin3b; KIAA0700paired amphipathic helix protein Sin3b; SIN3 homolog B, transcription regulator (yeast); SIN3 homolog B, transcriptional regulator (yeast); SIN3 homolog B, transcriptional regulator; Transcriptional corepressor Sin3b Sin3b|2810430C10Rik|transcriptional regulator, SIN3B (yeast)|paired amphipathic helix protein Sin3b|SIN3 homolog B, transcription regulator|histone deacetylase complex subunit Sin3b|transcriptional corepressor Sin3b|transcriptional regulator, SIN3 yeast homolog B
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Sin3b, check out the Sin3b Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Sin3b: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-SIN3B Antibody (A06424-1)
Hello CJ!
No publications found for A06424-1
*Do you have publications using this product? Share with us and receive a reward. Ask us for more details.
Recommended Resources
Here are featured tools and databases that you might find useful.
- Boster's Pathways Library
- Protein Databases
- Bioscience Research Protocol Resources
- Data Processing & Analysis Software
- Photo Editing Software
- Scientific Literature Resources
- Research Paper Management Tools
- Molecular Biology Software
- Primer Design Tools
- Bioinformatics Tools
- Phylogenetic Tree Analysis
Customer Reviews
Have you used Anti-SIN3B Antibody?
Submit a review and receive an Amazon gift card.
- $30 for a review with an image
Be the first to review Anti-SIN3B Antibody
*The first user to submit a review for a product is eligible for Boster's Innovating Scientists Reward, which gives product credits. This is in addition to the gift card reward.
Customer Q&As
Have a question?
Find answers in Q&As, reviews.
Can't find your answer?
Submit your question
