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Product Info Summary
| SKU: | A06464 |
|---|---|
| Size: | 80 µl |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | IF, WB |
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Product info
Product Name
Anti-SMARCD3 Antibody (N-term)
SKU/Catalog Number
A06464
Size
80 µl
Description
Boster Bio Anti-SMARCD3 Antibody (N-term) (Catalog # A06464). Tested in IF, WB application(s). This antibody reacts with Human.
Storage & Handling
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Cite This Product
Anti-SMARCD3 Antibody (N-term) (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06464)
Host
Rabbit
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
This SMARCD3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 27-60 amino acids from the N-terminal region of human SMARCD3.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A06464 is reactive to SMARCD3 in Human
Reconstitution
Calculated molecular weight
55016 Da
Background of SMARCD3
Plays a role in ATP dependent nucleosome remodeling by SMARCA4 containing complexes. Stimulates nuclear receptor mediated transcription. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron- specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post- mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A06464 is guaranteed for IF, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IF: 1:25
WB: 1:1000
Validation Images & Assay Conditions
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Fluorescent image of Hela cells stained with SMARCD3 Antibody (N-term). A06464 was diluted at 1:25 dilution. An Alexa Fluor 488-conjugated goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody (green). Cytoplasmic actin was counterstained with Alexa Fluor® 555 conjugated with Phalloidin (red).
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Western blot analysis of lysate from human heart tissue lysate, using SMARCD3 Antibody (N-term) (Cat. #A06464). A06464 was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug.
Protein Target Info & Infographic
Gene/Protein Information For SMARCD3 (Source: Uniprot.org, NCBI)
Gene Name
SMARCD3
Full Name
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3
Weight
55016 Da
Superfamily
SMARCD family
Alternative Names
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3, 60 kDa BRG-1/Brm-associated factor subunit C, BRG1-associated factor 60C, BAF60C, SMARCD3, BAF60C SMARCD3 BAF60C, CRACD3, Rsc6p SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3|60 kDa BRG-1/Brm-associated factor subunit C|BRG1-associated factor 60C|SWI/SNF complex 60 kDa subunit C|Swp73-like protein|chromatin remodeling complex BAF60C subunit|mammalian chromatin remodeling complex BRG1-associated factor 60C
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SMARCD3, check out the SMARCD3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SMARCD3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-SMARCD3 Antibody (N-term) (A06464)
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