Anti-SNAI 1 Monoclonal Antibody

Product Name

Anti-SNAI 1 Monoclonal Antibody

View all Snail Antibodies

SKU/Catalog Number

M00716

Size

100ul

Form

Liquid

Description

Boster Bio Anti-SNAI 1 Monoclonal Antibody catalog # M00716. Tested in ELISA, WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-SNAI 1 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00716)

Host

Mouse

Contents

Ascitic fluid containing 0.03% sodium azide.

Clonality

Monoclonal

Clone Number

6D2

Isotype

IgG

Immunogen

Purified recombinant fragment of human SNAI 1 expressed in E. Coli.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

M00716 is reactive to SNAI1 in Human

Applications

M00716 is guaranteed for ELISA, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

29.083kDa

Background of Snail

TRPC6, also known as TRP6, short transient receptor potential channel 6 and transient receptor potential cation channel subfamily C member 6, is thought to form a receptor-activated non-selective calcium permeant cation channel. TRPC6 is probably operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. It is activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C and may not to be activated by intracellular calcium store depletion. Defects in this gene are a cause of focal segmental glomerulosclerosis (FSGS). Expression of this protein has been reported in tissues such as placenta, lung, spleen, ovary, small intestine, and renal podocytes. Immunohistochemistry studies using polyclonal antibodies to this target have shown moderate to strong staining in cell types such as neurons, breast, respiratory, squamous and prostate epithelium, epidermis, placental trophoblasts, dendritic cells, and subsets of immune cells, and faint to moderate staining of adrenal, colon, ganglion cells, hepatocytes, heart, and testis.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:500-1:2000
ELISA 1:10000

Validation Images & Assay Conditions

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Figure 2. ELISA validation of SNAI1 using Anti-SNAI 1 Monoclonal Antibody (M00716).

ELISA analysis of SNAI 1 antibody.

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Figure 1. Western blotting validation for Anti-SNAI 1 Monoclonal Antibody M00716

Western Blot (WB) analysis using SNAI 1 Monoclonal Antibody against NTERA-2 cell lysate.
Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration

Gene/Protein Information For SNAI1 (Source: Uniprot.org, NCBI)

Alternative Names

Protein sna; Protein snail homolog 1; SLUGH2; SNA; SNAH; SNAHdJ710H13.1; SNAI1; snail 1 (drosophila homolog), zinc finger protein; snail 1 homolog; snail 1 zinc finger protein; snail 1, zinc finger protein; snail homolog 1 (Drosophila); Snail; zinc finger protein SNAI1 SNAI1 SLUGH2, SNA, SNAH, SNAIL, SNAIL1, dJ710H13.1 snail family transcriptional repressor 1 zinc finger protein SNAI1|protein sna|protein snail homolog 1|snail 1 homolog|snail 1 zinc finger protein|snail family zinc finger 1|snail homolog 1

For more info on SNAI1, check out the SNAI1 Infographic

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In this infographic, you will see the following information for SNAI1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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