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Product Info Summary
| SKU: | A03654 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-TCCR IL27RA Antibody
View all IL-27R alpha/WSX-1/TCCR Antibodies
SKU/Catalog Number
A03654
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-TCCR IL27RA Antibody (Catalog # A03654). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human.
Storage & Handling
TCCR antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-TCCR IL27RA Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03654)
Host
Rabbit
Contents
TCCR Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
TCCR antibody was raised against a synthetic peptide corresponding to amino acids near the amino terminus of human TCCR precursor. The immunogen is located within the first 50 amino acids of TCCR.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least three isoforms of KIF5 are known to exist; this antibody will recognize all three isoforms.
Reactive Species
A03654 is reactive to IL27RA in Human
Applications
A03654 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
69.474kDa
Background of IL-27R alpha/WSX-1/TCCR
Upon antigen challenge, T-helper cells differentiate into two functional distinct subsets, Th1 and Th2. Th1 cells produce IL-2, IFN-gamma and lymphotoxin-beta that augment cell mediated immune response while Th2 cells secrete IL-4, IL-5, and IL-10 that enhance humoral immunity. The function of T-helper cells is regulated by cytokines. A novel cytokine receptor was recently identified and cloned. It is a new member in the type I cytokine receptor family and designated TCCR for T-cell cytokine receptor and WSX-1. TCCR deficient mice had impaired Th1 responses to protein antigen challenge, including decreased levels of IFN-gamma and Th1-dependent antibody IgG2a. TCCR is predominately expressed in thymus, spleen, lymph notes and peripheral blood leukocytes.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
TCCR antibody can be used for detection of TCCR by Western blot at 1 μg/mL. An approximately 70 kDa band can be detected. Antibody can also be used for immunohistochemistry starting at 10 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of TCCR expression in human spleen tissue lysates with TCCR antibody at 1 μg/ml.
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Immunohistochemistry of TCCR in human spleen tissue with TCCR antibody at 10 μg/mL.
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Immunofluorescence of TCCR in A549 cells with TCCR antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For IL27RA (Source: Uniprot.org, NCBI)
Gene Name
IL27RA
Full Name
Interleukin-27 receptor subunit alpha
Weight
69.474kDa
Superfamily
type I cytokine receptor family
Alternative Names
class I cytokine receptor; CRL1IL-27R; Cytokine receptor-like 1; IL-27 R alpha; IL27R alpha; IL27R; IL27RA; IL-27Ra; IL-27R-alpha; interleukin 27 receptor, alpha; interleukin-27 receptor subunit alpha; TCCR; TCCRIL-27 receptor subunit alpha; T-cell cytokine receptor type 1; Type I T-cell cytokine receptor; WSX-1; WSX1IL-27R subunit alpha; zcytor1 IL27RA CRL1, IL-27RA, IL27R, TCCR, WSX1, zcytor1 interleukin 27 receptor subunit alpha interleukin-27 receptor subunit alpha|IL-27 receptor subunit alpha|IL-27R subunit alpha|IL-27R-alpha|T-cell cytokine receptor type 1|class I cytokine receptor|cytokine receptor WSX-1|cytokine receptor-like 1|interleukin 27 receptor, alpha|type I T-cell cytokine receptor
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on IL27RA, check out the IL27RA Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for IL27RA: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-TCCR IL27RA Antibody (A03654)
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No publications found for A03654
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Customer Reviews
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