Anti-TEM2 RASD2 Antibody

Product Name

Anti-TEM2 RASD2 Antibody

View all RASD2 Antibodies

SKU/Catalog Number

A06806

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-TEM2 RASD2 Antibody (Catalog # A06806). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

TEM2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-TEM2 RASD2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06806)

Host

Rabbit

Contents

TEM2 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

TEM2 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of the human TEM2. The immunogen is located within the last 50 amino acids of TEM2.

Reactive Species

A06806 is reactive to RASD2 in Human, Mouse, Rat

Observed Molecular Weight

68 kDa

Calculated molecular weight

30.4 kDa

Background of RASD2

Rhes, also known as tumor endothelial marker 2 (TEM2), is a small GTP-binding protein that is predominantly expressed in the striatal region of the brain. This protein belongs to the RASD subfamily of Ras-related GTP-binding protein superfamily and is thought to play a role in the normal development and function of the brain as mice lacking this gene showed increased anxiety levels and motor coordination deficits. Rhes was identified as TEM2 through analysis of genes whose expression was upregulated in tumor endothelium. Tumor endothelial markers are significantly up-regulated during angiogenesis and neoangiogenesis that are crucial for the growth of solid tumors. TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A06806 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

TEM2 antibody can be used for detection of TEM2 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

See full target information RASD2

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