Product Info Summary
SKU: | M00936 |
---|---|
Size: | 100ug/vial |
Reactive Species: | Human |
Host: | Mouse |
Application: | Flow Cytometry, IF, IHC |
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Product info
Product Name
Anti-Tenascin C (Stromal Marker For Epithelial Malignancy) Monoclonal Antibody
View all Tenascin C Antibodies
SKU/Catalog Number
M00936
Size
100ug/vial
Form
Liquid
Description
Boster Bio Anti-Tenascin C (Stromal Marker For Epithelial Malignancy) Monoclonal Antibody (Catalog # M00936). Tested in Flow Cytometry, IF, IHC applications. This antibody reacts with Human.
Storage & Handling
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Cite This Product
Anti-Tenascin C (Stromal Marker For Epithelial Malignancy) Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00936)
Host
Mouse
Contents
Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Clonality
Monoclonal
Clone Number
Clone: SPM319
Isotype
IgG1, kappa
Immunogen
Human breast carcinoma
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Does not cross-react with primate, avian or amphibian GR.
Reactive Species
M00936 is reactive to TNC in Human
Applications
M00936 is guaranteed for Flow Cytometry, IF, IHC Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
240.853kDa
Background of Tenascin C
In Western blotting, it reacts with two bands of ~MW of 210kDa and 300kDa, identified as two isoforms of Tenascin C. Specificity of This monoclonal antibody is validated by sequential immunoprecipitation with a PAb against Tenascin C. Tenascin C is a multifunctional, disulfide-linkedhexameric extracellular matrix glycoprotein expressed in association with mesenchymal epithelial interactions during development and in the neo-vasculature and stroma of undifferentiated tumors. In adults, it is restricted to certain epithelial-stromal interfaces and increases markedly in hyper-proliferative diseases and in stroma of many neoplasms, including gliomas, breast, squamous and lung carcinomas.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Reconsitution
Reconstitute with distilled water.
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Flow Cytometry (1-2ug/million cells)
Immunofluorescence (1-2ug/ml)
Immunohistochemistry (Formalin-fixed) (2-4ug/ml for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Validation Images & Assay Conditions
Click image to see more details
Formalin-fixed, paraffin-embedded human Lung Carcinoma stained with Anti-Tenascin C Mouse Monoclonal Antibody (SPM319).
Protein Target Info & Infographic
Gene/Protein Information For TNC (Source: Uniprot.org, NCBI)
Gene Name
TNC
Full Name
Tenascin
Weight
240.853kDa
Superfamily
tenascin family
Alternative Names
150-225; Cytotactin; Glioma-associated-extracellular matrix antigen; GMEM; GP 150-225; hexabrachion (tenascin C, cytotactin); hexabrachion (tenascin); Hexabrachion; HXB; HXBcytotactin; JI; MGC167029; Myotendinous antigen; neuronectin; Tenascin C; Tenascin J1; tenascin; tenascin-C isoform 14/AD1/16; Tenascin-C; TNC; TN-C; TNGP TNC 150-225, DFNA56, GMEM, GP, HXB, JI, TN, TN-C tenascin C tenascin|GP 150-225|cytotactin|deafness, autosomal dominant 56|glioma-associated-extracellular matrix antigen|hexabrachion (tenascin)|myotendinous antigen|neuronectin|tenascin-C additional domain 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TNC, check out the TNC Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TNC: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Tenascin C (Stromal Marker For Epithelial Malignancy) Monoclonal Antibody (M00936)
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No publications found for M00936
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