Anti-Tetraspanin-33 TSPAN33 Antibody

Product Name

Anti-Tetraspanin-33 TSPAN33 Antibody

View all Tspan33 Antibodies

SKU/Catalog Number

A13091

Size

100ul

Form

Liquid

Description

Boster Bio Anti-Tetraspanin-33 TSPAN33 Antibody catalog # A13091. Tested in WB,IHC applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Tetraspanin-33 TSPAN33 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A13091)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human Glypican-2

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A13091 is reactive to Tspan33 in Human, Mouse, Rat

Applications

A13091 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

31.55kDa

Background of Tspan33

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway By similarity.

Hu P., Mol. Cell. Biol. 22:8044-8055(2002).
Hirosawa M., DNA Res. 8:1-9(2001).
Collins J.E., Genome Biol. 5:RESEARCH84.1-RESEARCH84.11(2004).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:200-1:1000
IHC: 1:50-1:200

Validation Images & Assay Conditions

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Figure 1. Western blotting validation for Anti-Tetraspanin-33 TSPAN33 Antibody A13091

Western blot analysis of extracts of various cell lines

Gene/Protein Information For Tspan33 (Source: Uniprot.org, NCBI)

Alternative Names

hPen; PEN; Penumbra; proerythroblast new membrane; tetraspanin 33; tetraspanin-33; TSPAN33; tspan-33

For more info on Tspan33, check out the Tspan33 Infographic

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In this infographic, you will see the following information for Tspan33: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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