Anti-TFIIH p89 ERCC3 Monoclonal Antibody

Product Name

Anti-TFIIH p89 ERCC3 Monoclonal Antibody

View all XPB Antibodies

SKU/Catalog Number

M03103

Size

100ul

Form

Liquid

Description

Boster Bio Anti-TFIIH p89 ERCC3 Monoclonal Antibody catalog # M03103. Tested in WB applications. This antibody reacts with Bovine, Canine, Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-TFIIH p89 ERCC3 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M03103)

Host

Mouse

Contents

Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.

Clonality

Monoclonal

Clone Number

5D2

Isotype

IgG

Immunogen

Purified recombinant human TFIIH p89 (C-terminal) protein fragments expressed in E.coli.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

M03103 is reactive to ERCC3 in Bovine, Canine, Human, Mouse, Rat

Applications

M03103 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

89.278kDa

Background of XPB

Anti-Procalcitonin antibody detects human Procalcitonin. Procalcitonin is a peptide hormone mainly produced by the C cells of the thyroid and certain endocrine cells of the lung. Under normal expression conditions, procalcitonin is immediately cleaved into three specific fragments, a N terminal residue, calcitonin and katacalcin. Levels of unprocessed procalcitonin rise significantly after bacterial infection, trauma or shock. This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:1000-1:2000

Validation Images & Assay Conditions

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Figure 1. Western blotting validation for Anti-TFIIH p89 ERCC3 Monoclonal Antibody M03103

Western Blot (WB) analysis using TFIIH p89 Monoclonal Antibody against PC12

Gene/Protein Information For ERCC3 (Source: Uniprot.org, NCBI)

Alternative Names

Basic transcription factor 2 89 kDa subunit; BTF2 p89; BTF2; DNA excision repair protein ERCC-3; DNA repair protein complementing XP-B cells; EC 3.6.1; EC 3.6.4.12; ERCC3; excision repair cross-complementing rodent repair deficiency, complementationgroup 3 (xeroderma pigmentosum group B complementing); GTF2H; RAD25; TFIIH basal transcription factor complex 89 kDa subunit; TFIIH basal transcription factor complex helicase XPB subunit; TFIIH p89; TFIIH; Xeroderma pigmentosum group B-complementing protein; xeroderma pigmentosum, complementation group B; XPB; XPBC; XPBTFIIH 89 kDa subunit ERCC3 BTF2, GTF2H, RAD25, TFIIH, TTD2, XPB ERCC excision repair 3, TFIIH core complex helicase subunit general transcription and DNA repair factor IIH helicase subunit XPB|BTF2 p89|DNA excision repair protein ERCC-3|DNA repair helicase|DNA repair protein complementing XP-B cells|TFIIH 89 kDa subunit|TFIIH basal transcription factor complex 89 kDa subunit|TFIIH basal transcription factor complex helicase XPB subunit|TFIIH p89|TFIIH subunit XPB|basic transcription factor 2 89 kDa subunit|excision repair cross-complementation group 3|excision repair cross-complementing rodent repair deficiency, complementation group 3|xeroderma pigmentosum group B-complementing protein|xeroderma pigmentosum, complementation group B

For more info on ERCC3, check out the ERCC3 Infographic

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In this infographic, you will see the following information for ERCC3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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