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Product Info Summary
| SKU: | A08563 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-TGM5 Antibody
View all Transglutaminase 5 Antibodies
SKU/Catalog Number
A08563
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-TGM5 Antibody (Catalog # A08563). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
TGM5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-TGM5 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08563)
Host
Rabbit
Contents
TGM5 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
TGM5 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human TGM5. The immunogen is located within the last 50 amino acids of TGM5.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
TGM5 antibody is predicted to not cross-react with other TGase protein family members. Multiple isoforms of TGM5 are known to exist.
Reactive Species
A08563 is reactive to TGM5 in Human, Mouse, Rat
Applications
A08563 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
80.778kDa
Background of Transglutaminase 5
Transglutaminases (TGM) are a family of structurally and functionally related Ca2+-dependent enzymes (TGases) that stabilize protein assemblies through the formation of gamma-glutamyl-epsilon lysine crosslinks. TGases influence numerous biological processes, including blood coagulation, cell differentiation, fertilization and apoptosis. TGM5 belongs to the transglutaminase superfamily and catalyzes the cross-linking of proteins between glutamine and lysine residues, often resulting in stabilization of protein assemblies. TGM5 is also expressed in the human hair follicle. Defects in TGM5 are associated with acral peeling skin syndrome.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
TGM5 antibody can be used for detection of TGM5 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of TGM5 in rat heart tissue lysate with TGM5 antibody at (A) 1 and (B) 2 μg/mL.
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Immunohistochemistry of TGM5 in mouse heart tissue with TGM5 antibody at 2.5 μg/mL.
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Immunofluorescence of TGM5 in mouse heart tissue with TGM5 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For TGM5 (Source: Uniprot.org, NCBI)
Gene Name
TGM5
Full Name
Protein-glutamine gamma-glutamyltransferase 5
Weight
80.778kDa
Superfamily
transglutaminase superfamily
Alternative Names
EC 2.3.2.13; protein-glutamine gamma-glutamyltransferase 5; TG(X); TGase X; TGASE5; TGase-5; TGASEX; TGM6; TGMX; TGXMGC141907; transglutaminase 5; transglutaminase V; Transglutaminase X; transglutaminase-5 TGM5 PSS2, TGASE5, TGASEX, TGM6, TGMX, TGX transglutaminase 5 protein-glutamine gamma-glutamyltransferase 5|TG(X)|TGase X|TGase-5|transglutaminase V|transglutaminase X
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TGM5, check out the TGM5 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TGM5: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-TGM5 Antibody (A08563)
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No publications found for A08563
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Customer Reviews
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