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Product Info Summary
| SKU: | A18282 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | ELISA, IF, ICC, WB |
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Product info
Product Name
Anti-TGM7 Antibody
View all Transglutaminase 7/TGM7 Antibodies
SKU/Catalog Number
A18282
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-TGM7 Antibody (Catalog # A18282). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human, Mouse.
Storage & Handling
TGM7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-TGM7 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A18282)
Host
Rabbit
Contents
TGM7 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
TGM7 antibody was raised against a 13 amino acid synthetic peptide near the center of human TGM7. The immunogen is located within amino acids 460 - 510 of TGM7.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
TGM7 antibody is predicted to not cross-react with other TGase protein family members. At least two isoforms of TGM7 are known to exist; this antibody will recognize both isoforms.
Reactive Species
A18282 is reactive to TGM7 in Human, Mouse
Applications
A18282 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
79.941kDa
Background of Transglutaminase 7/TGM7
Transglutaminases (TGM) are a family of structurally and functionally related Ca2+-dependent enzymes (TGases) that stabilize protein assemblies through the formation of gamma-glutamyl-epsilon lysine crosslinks. TGases influence numerous biological processes, including blood coagulation, cell differentiation, fertilization and apoptosis. TGM7 belongs to the transglutaminase superfamily and is also thought to catalyze the cross-linking of proteins, often resulting in stabilization of protein assemblies. Little is known of the role of TGM7, but defects in the highly related protein TGM5 are associated with acral peeling skin syndrome.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
TGM7 antibody can be used for detection of TGM7 by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μg/mL. For immunofluorescence start at 10 μg/mL.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of TGM7 in human lung tissue lysate with TGM7 antibody at 1 μg/mL.
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Immunocytochemistry of TGM7 in A549 cells with TGM7 antibody at 2.5 μg/mL.
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Immunofluorescence of TGM7 in A549 cells with TGM7 antibody at 10 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For TGM7 (Source: Uniprot.org, NCBI)
Gene Name
TGM7
Full Name
Protein-glutamine gamma-glutamyltransferase Z
Weight
79.941kDa
Superfamily
transglutaminase superfamily
Alternative Names
protein-glutamine gamma-glutamyltransferase Z; TG(Z); TGase Z; TGase-7; TGM7; TGMZ; TGMZEC 2.3.2.13; TGZ; Transglutaminase 7; Transglutaminase Z; transglutaminase-7 TGM7 TGMZ transglutaminase 7 protein-glutamine gamma-glutamyltransferase Z|TG(Z)|TGZ|TGase Z|TGase-7|transglutaminase Z
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TGM7, check out the TGM7 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TGM7: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-TGM7 Antibody (A18282)
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No publications found for A18282
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Customer Reviews
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