Anti-Thyroglobulin TG Antibody

Product Name

Anti-Thyroglobulin TG Antibody

View all Thyroglobulin Antibodies

SKU/Catalog Number

A00359

Size

100ul

Form

Liquid

Description

Boster Bio Anti-Thyroglobulin TG Antibody catalog # A00359. Tested in ELISA, IHC applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Thyroglobulin TG Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00359)

Host

Rabbit

Contents

PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthetic peptide from human Thyroglobulin protein.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A00359 is reactive to TG in Human, Mouse, Rat

Applications

A00359 is guaranteed for ELISA, IHC Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

304.79kDa

Background of Thyroglobulin

This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

David A. Jans, J. Biol. Chem., Nov 1996; 271: 30781.
Eugene Estella, Diabetes, Aug 2006; 55: 2212 - 2219.
Yong Gu, J. Biol. Chem., May 1996; 271: 10816.
Jiuru Sun, J. Biol. Chem., Nov 1996; 271: 27802.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

IHC-P 1:50-300
ELISA 1:5000-20000

Validation Images & Assay Conditions

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Figure 1. Immunohistochemistry validation of TG using Anti-Thyroglobulin TG Antibody (A00359).

Immunohistochemical analysis of paraffin-embedded human-thyroid

Gene/Protein Information For TG (Source: Uniprot.org, NCBI)

Alternative Names

AITD3; AITD3TGN; cog; TDH3; Tg; TGN; Thyroglobulin TG AITD3N, TG thyroglobulin thyroglobulin

For more info on TG, check out the TG Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for TG: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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