Product Info Summary
| SKU: | A06637 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-TIM-4 TIMD4 Antibody
SKU/Catalog Number
A06637
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-TIM-4 TIMD4 Antibody (Catalog # A06637). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
TIM-4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-TIM-4 TIMD4 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06637)
Host
Rabbit
Contents
TIM-4 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
TIM-4 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human TIM-4. The immunogen is located within the last 50 amino acids of TIM-4.
Reactive Species
A06637 is reactive to TIMD4 in Human, Mouse, Rat
Observed Molecular Weight
68 kDa
Calculated molecular weight
41.6 kDa
Background of TIMD4
The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors that are involved in the regulation of T helper (Th) -1 and -2 cell-mediated immunity. TIM-4, which is preferentially expressed on macrophages and dendritic cells, is the natural ligand of TIM-1, and this binding leads to T-cell expansion and cytokine production. Unlike other members of the TIM family, TIM-4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain. The TIM-4 gene maps to a locus associated with predisposition to asthma in both mice and humans and with its connection to TIM-1-triggered Th2 responsiveness, may be considered as a candidate disease/predisposition gene for asthma.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A06637 is guaranteed for ELISA, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
TIM-4 antibody can be used for the detection of TIM-4 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of TIM-4 in Jurkat lysate with TIM-4 antibody at (A) 1 and (B) 2 μg/mL.
Specific Publications For Anti-TIM-4 TIMD4 Antibody (A06637)
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