Product Info Summary
SKU: | A12570 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IF, IHC, ICC, WB |
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Product info
Product Name
Anti-TIMM8B Antibody
SKU/Catalog Number
A12570
Size
100ul
Form
Liquid
Description
Boster Bio Anti-TIMM8B Antibody catalog # A12570. Tested in WB,IHC,ICC/IF applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-TIMM8B Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A12570)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from C-terminal of human ATBP3.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A12570 is reactive to TIMM8B in Human, Mouse, Rat
Applications
A12570 is guaranteed for IF, IHC, ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
9.344kDa
Background of TIMM8B
Plays a central role in 2-thiolation of mcm5S2U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.
Yousef G.M., Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases.
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Beausoleil S.A., Nat. Biotechnol. 24:1285-1292(2006).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
IHC: 1:50-1:100
ICC/IF: 1:50-1:100
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Western blotting validation for Anti-TIMM8B Antibody A12570
Western blot analysis of extracts of various cell linesProtein Target Info & Infographic
Gene/Protein Information For TIMM8B (Source: Uniprot.org, NCBI)
Gene Name
TIMM8B
Full Name
Mitochondrial import inner membrane translocase subunit Tim8 B
Weight
9.344kDa
Superfamily
small Tim family
Alternative Names
DDP2DDP-like protein; DDPL; Deafness dystonia protein 2; FLJ21744; MGC102866; MGC117373; mitochondrial import inner membrane translocase subunit Tim8 B; TIM8Btranslocase of inner mitochondrial membrane 8 (yeast) homolog B; translocase of inner mitochondrial membrane 8 homolog B (yeast) TIMM8B DDP2, TIM8B translocase of inner mitochondrial membrane 8 homolog B mitochondrial import inner membrane translocase subunit Tim8 B|DDP-like protein|deafness dystonia protein 2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TIMM8B, check out the TIMM8B Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TIMM8B: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-TIMM8B Antibody (A12570)
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No publications found for A12570
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