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Product Info Summary
| SKU: | A03965-2 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IF, ICC, WB |
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Product info
Product Name
Anti-TIRP TICAM2 Antibody
SKU/Catalog Number
A03965-2
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-TIRP TICAM2 Antibody (Catalog # A03965-2). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human.
Storage & Handling
TIRP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-TIRP TICAM2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03965-2)
Host
Rabbit
Contents
TIRP Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
TIRP antibody was raised against a peptide corresponding to 16 amino acids at the C-terminus of human TIRP. The immunogen is located within the last 50 amino acids of TIRP.
Reactive Species
A03965-2 is reactive to TICAM2 in Human
Observed Molecular Weight
68 kDa
Calculated molecular weight
26.9 kDa
Background of TICAM2
TIRP is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TIRP, along with other molecules such as TRIF, MAL, and MyD88, serves as an adaptor protein that allows for the interaction and activation of the IL-1R-associated kinase (IRAK) family, the subsequent activation of TNF receptor associated factor (TRAF)-6, and ultimately the activation of NF-κB. Expression of TIRP appears to be essential for TLR4 signalling.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A03965-2 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
TIRP antibody can be used for detection of TIRP by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 10 μg/mL. For immunofluorescence start at 10 μg/mL.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of TIRP in PC-3 cell lysate with TIRP antibody at 1 μg/mL.
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Immunocytochemistry of TIRP in Raji cells with TIRP antibody at 10 μg/mL.
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Immunofluorescence of TIRP in Raji cells with TIRP antibody at 10 μg/mL.
Specific Publications For Anti-TIRP TICAM2 Antibody (A03965-2)
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