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Product Info Summary
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Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-TLR2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00131-1)
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
This TLR2 Antibody is generated from a mouse immunized with a recombinant protein .
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
M00131-1 is reactive to TLR2 in Human
M00131-1 is guaranteed for WB Boster Guarantee
Background of TLR2
Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6.
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.
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Validation Images & Assay Conditions
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All lanes : Anti-TLR2 Antibody at 1:500-1:1000 dilution
Lane 1: Ramos whole cell lysate
Lane 2: A549 whole cell lysate
Lane 3: MDA-MB-231 whole cell lysate
Lysates/proteins at 20 µg per lane.
Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.
Predicted band size : 85 kDa
Blocking/Dilution buffer: 5% NFDM/TBST.
Gene/Protein Information For TLR2 (Source: Uniprot.org, NCBI)
Toll-like receptor 2
Toll-like receptor family
CD282 antigen; CD282; TIL4CD282; TLR2; toll/interleukin 1 receptor-like 4; Toll/interleukin-1 receptor-like protein 4; toll-like receptor 2 TLR2 CD282, TIL4 toll like receptor 2 toll-like receptor 2|toll/interleukin-1 receptor-like protein 4*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".
For more info on TLR2, check out the TLR2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TLR2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected]
M00131-1 has been cited in 1 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
Feng S,Ju L,Shao Z,Grzanna M,Jia L,Liu M.Therapeutic Effect of C-C Chemokine Receptor Type 1 (CCR1) Antagonist BX471 on Allergic Rhinitis.J Inflamm Res.2020 Jul 21;13:343-356.doi:10.2147/JIR.S254717.PMID: 32801828;PMCID:PMC7398876.
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