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Product Info Summary
| SKU: | A11164 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-TLX2 Antibody
SKU/Catalog Number
A11164
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-TLX2 Antibody (Catalog # A11164). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
TLX2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-TLX2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A11164)
Host
Rabbit
Contents
TLX2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
TLX2 antibody was raised against an 18 amino acid peptide near the amino terminus of human TLX2. The immunogen is located within amino acids 20 - 70 of TLX2.
Cross-reactivity
TLX2 antibody is predicted to not cross-react with other TLX proteins.
Reactive Species
A11164 is reactive to TLX2 in Human, Mouse, Rat
Observed Molecular Weight
68 kDa
Calculated molecular weight
30.3 kDa
Background of TLX2
The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. TLX2, also known as homeobox11-like 1 (HOX11L1), is a DNA-binding nuclear transcription factor that appears to be crucial for the development of the peripheral nervous system. TLX2 is a downstream target of regulation by both PHOX2A and PHOX2B proteins during intestinal neuronal differentiation. In humans, loss-of-function of TLX2 may play a role in tumorigenesis of gastrointestinal stromal tumors.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A11164 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
TLX2 antibody can be used for detection of TLX2 by Western blot at 0.5 - 1 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of TLX2 in rat brain tissue lysate with TLX2 antibody at (A) 0.5 and (B) 1 μg/mL.
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Immunohistochemistry of TLX2 in rat brain tissue with TLX2 antibody at 2.5 μg/ml.
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Immunofluorescence of TLX2 in rat brain tissue with TLX2 antibody at 20 μg/ml.
Specific Publications For Anti-TLX2 Antibody (A11164)
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