Anti-TMEM70 Antibody

Product Name

Anti-TMEM70 Antibody

View all TMEM70 Antibodies

SKU/Catalog Number

A06360

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-TMEM70 Antibody (Catalog # A06360). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

TMEM70 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-TMEM70 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06360)

Host

Rabbit

Contents

TMEM70 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

TMEM70 antibody was raised against a 14 amino acid synthetic peptide near the center of human TMEM70. The immunogen is located within amino acids 150 - 200 of TMEM70.

Reactive Species

A06360 is reactive to TMEM70 in Human, Mouse, Rat

Observed Molecular Weight

68 kDa

Calculated molecular weight

29.0 kDa

Background of TMEM70

TMEM70 is a recently identified mitochondrial protein that is thought to play a role in the biogenesis of the ATP synthase in higher eukaryotes. Mutations in this gene result in early neonatal onset of hypotonia, hypertrophic cardiomyopathy, lactic acidos and 3-methylglutaconic aciduria (3-MGC-uria), and usually cause death within the first six weeks of life, although some patients survive much longer. Little is known of the role of TMEM70, but it is conserved across multicellular eukaryotic organisms. It contains a conserved DUF1301 domain and two putative transmembrane regions.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A06360 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

TMEM70 antibody can be used for detection of TMEM70 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

See full target information TMEM70

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