Anti-Toll-like receptor 6 TLR6 Antibody

Product Name

Anti-Toll-like receptor 6 TLR6 Antibody

View all TLR6 Antibodies

SKU/Catalog Number

A01914

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Toll-like receptor 6 TLR6 Antibody (Catalog # A01914). Tested in ELISA, WB, ICC applications. This antibody reacts with Human, Mouse.

Storage & Handling

TLR6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-Toll-like receptor 6 TLR6 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01914)

Host

Rabbit

Contents

TLR6 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

TLR6 antibody was raised against a peptide corresponding to 15 amino acids near the amino terminus of human TLR6. The immunogen is located within amino acids 160 - 210 of TLR6.

Cross-reactivity

This TLR6 antibody is predicted to have no cross-reactivity to other members of the TLR protein family.

Reactive Species

A01914 is reactive to TLR6 in Human, Mouse

Observed Molecular Weight

68 kDa

Calculated molecular weight

91.9 kDa

Background of TLR6

Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors so the organism can respond to potential infection. TLR6 was first identified as a close homolog of TLR1, sharing 69% sequence identify. Like TLR1, TLR6 can form heterodimers with TLR2, and these TLR6:TLR2 dimers coordinate macrophage activation by Gram-positive bacteria and the yeast cell wall particle zymosan. Activation of these complexes not only initiates pro-inflammatory cascades, but also can lead to apoptotic responses.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A01914 is guaranteed for ELISA, ICC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

TLR6 antibody can be used for detection of TLR6 by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 10 μg/mL.
Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

See full target information TLR6

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