Anti-Transmembrane protein 88 TMEM88 Antibody

Product Name

Anti-Transmembrane protein 88 TMEM88 Antibody

View all TMEM88 Antibodies

SKU/Catalog Number

A12951

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Transmembrane protein 88 TMEM88 Antibody (Catalog # A12951). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

TMEM88 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-Transmembrane protein 88 TMEM88 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A12951)

Host

Rabbit

Contents

TMEM88 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

TMEM88 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human TMEM88. The immunogen is located within amino acids 110 - 160 of TMEM88.

Cross-reactivity

At least two isoforms of TMEM88 are known to exist; this antibody will recognize both isoforms.

Reactive Species

A12951 is reactive to TMEM88 in Human, Mouse, Rat

Observed Molecular Weight

68 kDa

Calculated molecular weight

17.3 kDa

Background of TMEM88

Transmembrane protein 88 (TMEM88) is a two-transmembrane-type protein whose C-terminal tail has been shown to bind the PDZ domain of Dishevelled (Dvl), one of the key components in Wnt signaling pathways. TMEM88 attentuated the Wnt/beta-catenin signaling induced by Wnt-1 ligand in a dose-dependent manner and knockdown of TMEM88 by RNAi increased Wnt activity, suggesting that TMEM88 plays a role in regulating Wnt signaling in a context-dependent manner.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A12951 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

TMEM88 antibody can be used for detection of TMEM88 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

See full target information TMEM88

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