Anti-TRESK KCNK18 Antibody

KCNK18 antibody

Boster Bio Anti-TRESK KCNK18 Antibody (Catalog # A07164). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A07164
Size: 0.1 mg
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: ELISA, IF, IHC-P, WB

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Product Name

Anti-TRESK KCNK18 Antibody

View all KCNK18 Antibodies

SKU/Catalog Number

A07164

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-TRESK KCNK18 Antibody (Catalog # A07164). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

TRESK antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-TRESK KCNK18 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A07164)

Host

Rabbit

Contents

TRESK Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

TRESK antibody was raised against a 17 amino acid synthetic peptide from near the center of human TRESK. The immunogen is located within amino acids 210 - 260 of TRESK.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A07164 is reactive to KCNK18 in Human, Mouse, Rat

Applications

A07164 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Background of KCNK18

TRESK (TWIK-related spinal cord K+ channel) is a two-pore domain K+ channel that induces outward rectification and functions as a background K+ channel that is abundantly expressed in the spinal cord, thymus, spleen, and leukemic T-lymphocytes. TRESK is activated by increased cytoplasmic calcium concentration through calcineurin as well as by acetylcholine and histamine. It has been suggested that TRESK is linked to acute and chronic pain by activation of calcineurin. Other studies indicate that TRESK may play a role in the regulation of T-cell function and could be an excellent target to treat T-cell originated immune dysfunction.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

TRESK antibody can be used for detection of TRESK by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL. Antibody validated: Western Blot in rat samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Validation Images & Assay Conditions

Gene/Protein Information For KCNK18 (Source: Uniprot.org, NCBI)

Uniprot ID

Q7Z418

Gene ID

338567

Gene Name

KCNK18

Full Name

Potassium channel subfamily K member 18

Weight

43.671kDa

Superfamily

two pore domain potassium channel (TC 1.A.1.8) family

Alternative Names

K2p18.1; potassium channel subfamily K member 18; potassium channel, subfamily K, member 18; TRESK2; TRESK-2; TRESKTWIK-related spinal cord potassium channel; TRIKMGR13; TWIK-related individual K+ channel; TWIK-related individual potassium channel; TWIK-related spinal cord K+ channel KCNK18 K2p18.1, MGR13, TRESK, TRESK-2, TRESK2, TRIK potassium two pore domain channel subfamily K member 18 potassium channel subfamily K member 18|TWIK-related individual K+ channel|TWIK-related individual potassium channel|TWIK-related spinal cord K+ channel|TWIK-related spinal cord potassium channel|potassium channel, subfamily K, member 18|potassium channel, two pore domain subfamily K, member 18

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on KCNK18, check out the KCNK18 Infographic

KCNK18 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for KCNK18: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected]

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Size

Total: $404

SKU:A07164

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A07164
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$404.00

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