Anti-TRIM29 (Lung Squamous Cell Carcinoma Marker) Monoclonal Antibody

Product Name

Anti-TRIM29 (Lung Squamous Cell Carcinoma Marker) Monoclonal Antibody

View all TRIM29 Antibodies

SKU/Catalog Number

M04472

Size

100ug/vial

Form

Liquid

Description

Boster Bio Anti-TRIM29 (Lung Squamous Cell Carcinoma Marker) Monoclonal Antibody (Catalog # M04472). Tested in WB applications. This antibody reacts with Human.

Storage & Handling

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Cite This Product

Anti-TRIM29 (Lung Squamous Cell Carcinoma Marker) Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M04472)

Host

Mouse

Contents

Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Clonality

Monoclonal

Clone Number

Clone: TRIM29/1042

Isotype

IgG2b, kappa

Immunogen

Recombinant fragment (126 Amino acid residues between aa 1-200) of human TRIM29 protein

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

Does not cross-react with primate, avian or amphibian GR.

Reactive Species

M04472 is reactive to TRIM29 in Human

Applications

M04472 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

65.835kDa

Background of TRIM29

This monoclonal antibody recognizes a 66kDa protein, which is identified as Tripartite motif-containing protein 29 (TRIM29). It interacts with the intermediate filament protein vimentin, a substrate for the PKC family of protein kinases, and with hPKCI-1, an inhibitor of the PKCs. TRIM29 protein contains both zinc finger and leucine zipper motifs, suggesting that the it may form homodimers and possibly associate with DNA. High expression of TRIM29 has been reported in gastric cancer and pancreatic cancer, and correlates with enhanced tumor growth and lymph node metastasis. TRIM29 is also able to distinguish lung squamous cell carcinoma from lung adenocarcinoma with ~90% positive accuracy, when used in a panel with TTF-1, p63, CK5/6, and Napsin-A antibodies.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Reconstitute with distilled water.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western Blot (1-2ug/ml)
Optimal dilution for a specific application should be determined.

Validation Images & Assay Conditions

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Western Blot analysis of TRIM29 Recombinant protein fragment & A431 cell lysate using Anti-TRIM29 Monoclonal Antibody (TRIM29/1042).

Gene/Protein Information For TRIM29 (Source: Uniprot.org, NCBI)

Alternative Names

Ataxia telangiectasia group D-associated protein; ATDC ataxia-telangiectasia group D-associated protein; ATDC; FLJ36085; tripartite motif containing 29; tripartite motif protein TRIM29; tripartite motif-containing 29; tripartite motif-containing protein 29 TRIM29 ATDC tripartite motif containing 29 tripartite motif-containing protein 29|ataxia-telangiectasia group D-associated protein|tripartite motif protein TRIM29

For more info on TRIM29, check out the TRIM29 Infographic

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In this infographic, you will see the following information for TRIM29: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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