Anti-TRIM30 Antibody

Product Name

Anti-TRIM30 Antibody

View all TRIM30 Antibodies

SKU/Catalog Number

A33062

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-TRIM30 Antibody (Catalog # A33062). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Mouse.

Storage & Handling

TRIM30 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-TRIM30 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A33062)

Host

Rabbit

Contents

TRIM30 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

TRIM30 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of the mouse TRIM30. The immunogen is located within amino acids 250 - 300 of TRIM30.

Reactive Species

A33062 is reactive to TRIM30 in Mouse

Observed Molecular Weight

68 kDa

Calculated molecular weight

57.3 kDa

Background of TRIM30

TRIM30 belongs to a family of the tripartite motif (TRIM) proteins involved in the regulation of cell proliferation, differentiation, development, oncogenesis, apoptosis and antiviral responses. The TRIM protein family is an expanding family of RING ('really interesting new gene') proteins, also known as RBCC proteins as they contain an RBCC motif, which comprises a RING domain, one or two B-boxes and a predicted coiled-coil region. Studies have shown that some TRIM family members are critical to innate immunity; TRIM5, TRIM19 and TRIM25, for example, have been shown to restrict viral infection. A recent study shows that TRIM30 functions as a negative modulator of the TLR signaling pathway, by targeting TAB2 and TAB3, and contributes to the inhibition of TLR-mediated NF-κB activation. The importance of TRIM30 in the attenuation or termination of NF-κB activation suggests that targeting of TAB2 and TAB3 by TRIM30α may be a mechanism for modulating many types of immune responses.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A33062 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Recommend Dilution

TRIM30 antibody can be used for detection of TRIM30 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 10 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in mouse samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

See full target information TRIM30

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