Anti-TROP-2 (F167) TACSTD2 Antibody

Product Name

Anti-TROP-2 (F167) TACSTD2 Antibody

View all TROP-2 Antibodies

SKU/Catalog Number

A03569-1

Size

100ul

Form

Liquid

Description

Boster Bio Anti-TROP-2 (F167) TACSTD2 Antibody catalog # A03569-1. Tested in WB,IHC applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-TROP-2 (F167) TACSTD2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03569-1)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human Rap1GAP

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A03569-1 is reactive to TACSTD2 in Human, Mouse, Rat

Applications

A03569-1 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

35.709kDa

Background of TROP-2

Component of the spliceosome A complex. Regulates alternative splicing of a number of mRNAs. May modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. May both positively and negatively regulate aopotosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis.

Bader S., Submitted (APR-1996) to the EMBL/GenBank/DDBJ databases.
Timmer T., Genomics 60:238-240(1999).
Oh J.J., Nucleic Acids Res. 27:4008-4017(1999).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Innovating Scientists Reward

If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.

Submit A Review

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:1000
IHC: 1:50-1:200

Validation Images & Assay Conditions

Click image to see more details

Western blot (WB) analysis of TROP-2 (F167) pAb at 1:500 dilution Lane1:3T3-L1 whole cell lysate(40ug) Lane2:The Skin tissue lysate of Rat(40ug) Lane3:A375 whole cell lysate(40ug) Lane4:Hela whole cell lysate(40ug)

Gene/Protein Information For TACSTD2 (Source: Uniprot.org, NCBI)

Alternative Names

Cell surface glycoprotein Trop-2; EGP1; EGP-1; epithelial glycoprotein-1; GA733-1; GA733-1GP50; gastrointestinal tumor-associated antigen GA7331; gp50; M1S1cell surface glycoprotein TROP2; Membrane component chromosome 1 surface marker 1; membrane component, chromosome 1, surface marker 1; Pancreatic carcinoma marker protein GA733-1; pancreatic carcinoma marker protein GA7331,40kD glycoprotein, identified by monoclonal GA733; T16; TACSTD2; TROP2; TROP-2; TROP2GA7331; tumor-associated calcium signal transducer 2 TACSTD2 EGP-1, EGP1, GA733-1, GA7331, GP50, M1S1, TROP2 tumor associated calcium signal transducer 2 tumor-associated calcium signal transducer 2|40kD glycoprotein, identified by monoclonal antibody GA733|cell surface glycoprotein TROP2|cell surface glycoprotein Trop-2|epithelial glycoprotein-1|gastrointestinal tumor-associated antigen GA7331|membrane component, chromosome 1, surface marker 1|pancreatic carcinoma marker protein GA733-1|pancreatic carcinoma marker protein GA7331|trophoblast cell surface antigen 2|truncated TACSTD2

For more info on TACSTD2, check out the TACSTD2 Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for TACSTD2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Take me to the TACSTD2 Infographic

Here are featured tools and databases that you might find useful.

• Boster's Pathways Library
• Protein Databases
• Bioscience Research Protocol Resources
• Data Processing & Analysis Software
• Photo Editing Software
• Scientific Literature Resources
• Research Paper Management Tools
• Molecular Biology Software
• Primer Design Tools
• Bioinformatics Tools
• Phylogenetic Tree Analysis