Anti-TRP1 TYRP1 Antibody

TYRP1 antibody

Boster Bio Anti-TRP1 TYRP1 Antibody catalog # A01959. Tested in WB,ICC,IHC,IP applications. This antibody reacts with Human.

Product Info Summary

SKU: A01959
Size: 100ul
Reactive Species: Human
Host: Rabbit
Application: IP, IHC, ICC, WB

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Product Name

Anti-TRP1 TYRP1 Antibody

View all TYRP1 Antibodies

SKU/Catalog Number

A01959

Size

100ul

Form

Liquid

Description

Boster Bio Anti-TRP1 TYRP1 Antibody catalog # A01959. Tested in WB,ICC,IHC,IP applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-TRP1 TYRP1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01959)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human IBP5 protein.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A01959 is reactive to TYRP1 in Human

Applications

A01959 is guaranteed for IP, IHC, ICC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

60.724kDa

Background of TYRP1

Cullins assemble a potentially large number of ubiquitin ligases by binding to the RING protein ROC1 to catalyse polyubiquitination, as well as binding to various specificity factors to recruit substrates. Cullin 5 is a component of E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Cullin 5 seems to be involved proteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. Cullin 5 may form a cell surface vasopressin receptor. Cullin 5 is part of a E3 ubiquitin ligase complex with elongin BC complex (TCEB1 and TCEB2), RBX1 and MUF1, complexes with elongin BC complex (TCEB1 and TCEB2), RXB1 and TCEB3 or SOCS1 or WSB1; elongin BC complex (TCEB1 and TCEB2), RBX1 and VHL; elongin BC complex (TCEB1 and TCEB2), RBX1, adenovirus type 5 E1B-55kDa protein and adenovirus type 5 E4-orf6. Cullin 5 Interacts with RBX1 and RNF7.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:2,000
ICC: 1:50-1:100
IHC: 1:50-1:200
IP: 1:10-1:50

Validation Images & Assay Conditions

Gene/Protein Information For TYRP1 (Source: Uniprot.org, NCBI)

Gene Name

TYRP1

Full Name

5,6-dihydroxyindole-2-carboxylic acid oxidase

Weight

60.724kDa

Superfamily

tyrosinase family

Alternative Names

b-PROTEIN; CAS25,6-dihydroxyindole-2-carboxylic acid oxidase; Catalase B; CATB; EC 1.14.18; EC 1.14.18.-; EC 1.14.18.1; Glycoprotein 75; GP75DHICA oxidase; Melanoma antigen gp75; TRP-1; TRPTYRP; tyrosinase-related protein 1TRP1; TYRRP TYRP1 CAS2, CATB, GP75, OCA3, TRP, TRP1, TYRP, b-PROTEIN tyrosinase related protein 1 5,6-dihydroxyindole-2-carboxylic acid oxidase|DHICA oxidase|catalase B|glycoprotein 75|melanoma antigen gp75

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on TYRP1, check out the TYRP1 Infographic

TYRP1 infographic

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In this infographic, you will see the following information for TYRP1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A01959-100ul

100ul

$405

Free Secondary Antibody

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A01959
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$405.00

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