Product Info Summary
| SKU: | A03078 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-TSC22 domain family protein 3 TSC22D3 Antibody
SKU/Catalog Number
A03078
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-TSC22 domain family protein 3 TSC22D3 Antibody (Catalog # A03078). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.
Storage & Handling
Antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-TSC22 domain family protein 3 TSC22D3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03078)
Host
Rabbit
Contents
TSC22D3 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Rabbit polyclonal TSC22D3 antibody was raised against a 16 amino acid peptide near the amino terminus of human TSC22D3. The immunogen is located within amino acids 40 - 90 of TSC22D3.
Reactive Species
A03078 is reactive to TSC22D3 in Human, Mouse
Observed Molecular Weight
68 kDa
Calculated molecular weight
14.8 kDa
Background of TSC22D3
The TSC22 domain family member 3 protein (TSC22D3) is a leucine zipper protein that functions as a transcriptional regulator. The expression of TSC22D3 is stimulated by glucocorticoids and IL-10 and is thought to play a key role in the anti-inflammatory and immunosuppressive effects of these molecules. TSC22D3 can physically interact with and inhibit the activities of key inflammatory signaling mediators such NF-κB and AP-1. TSC22D3 functions as a transcriptional co-activator for various nuclear receptors and NF-κB. It has also been shown to be involved in the differentiation of mesenchymal stem cells towards osteoblasts and bone formation.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A03078 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
TSC22D3 antibody can be used for detection of TSC22D3 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of TSC22D3 in human small intestine tissue lysate with TSC22D3 antibody at (A) 1 and (B) 2 μg/mL.
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Immunohistochemistry of TSC22D3 in human small intestine tissue with TSC22D3 antibody at 5 μg/ml.
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Immunofluorescence of TSC22D3 in human small intestine tissue with TSC22D3 antibody at 20 μg/ml.
Specific Publications For Anti-TSC22 domain family protein 3 TSC22D3 Antibody (A03078)
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