Anti-UHRF1-binding protein 1 UHRF1BP1 Antibody

Product Name

Anti-UHRF1-binding protein 1 UHRF1BP1 Antibody

View all UHRF1BP1 Antibodies

SKU/Catalog Number

A12200

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-UHRF1-binding protein 1 UHRF1BP1 Antibody (Catalog # A12200). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.

Storage & Handling

UHRF1BP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-UHRF1-binding protein 1 UHRF1BP1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A12200)

Host

Rabbit

Contents

UHRF1BP1 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

UHRF1BP1 antibody was raised against a 17 amino acid synthetic peptide near the center of human UHRF1BP1. The immunogen is located within amino acids 890 - 940 of UHRF1BP1.

Cross-reactivity

UHRF1BP1 antibody is predicted to not cross-react with UHRF1BP1L

Reactive Species

A12200 is reactive to UHRF1BP1 in Human, Mouse

Calculated molecular weight

159.5 kDa

Background of UHRF1BP1

The Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1 (UHRF1BP1), also known as ICBP90, is a transcription and cell cycle regulator. It specifically binds to the histone H3 N-terminal tail when methylated on K9 by two functional domains, a PHD finger that defines the binding specificity and an SRA (SET- and RING-associated) domain that promotes binding activity. UHRF1BP1 is required for proper heterochromatin formation in mammalian cells. Furthermore, UHRF1BP1 is thought to be a pivotal target for the ERK1/2 signaling pathway to control the proliferation of Jurkat T cells.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A12200 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

UHRF1BP1 antibody can be used for detection of UHRF1BP1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human and mouse samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Validation Images & Assay Conditions

See full target information UHRF1BP1

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