Product Info Summary
SKU: | A08157 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human |
Host: | Rabbit |
Application: | ELISA, IHC-P |
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Product info
Product Name
Anti-VARP ANKRD27 Antibody
SKU/Catalog Number
A08157
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-VARP ANKRD27 Antibody (Catalog # A08157). Tested in ELISA, IHC-P applications. This antibody reacts with Human.
Storage & Handling
VARP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-VARP ANKRD27 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08157)
Host
Rabbit
Contents
VARP Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
SK7
Isotype
IgG
Immunogen
VARP antibody was raised against a 15 amino acid synthetic peptide near the center of human VARP. The immunogen is located within amino acids 640 - 690 of VARP.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least four isoforms of ZBTB4 are known to exist; this antibody will only recognize the longest isoform. This antibody is predicted to not cross-react with other ZBTB protein family members.
Reactive Species
A08157 is reactive to ANKRD27 in Human
Applications
A08157 is guaranteed for ELISA, IHC-P Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
116.984kDa
Background of ANKRD27
The VPS9 ankyrin repeat protein (VARP) binds to the Rab21, a guanine nucleotide exchange factor that plays an essential role in endocytic trafficking. VARP localizes to early endosomes and is thought to regulate endosome dynamics. VARP also interacts with TI-VAMP/VAMP7, a vesicular SNARE that mediates an exocytic pathway that is crucial to neurite growth. Depletion of VARP by RNA interference impairs neurite growth, suggesting that VARP is a positive regulator of neurite growth.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
VARP antibody can be used for detection of VARP by Immunohistochemistry at 5 μg/mL.
Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
Click image to see more details
Immunohistochemistry of VARP in human small intestine with VARP antibody at 5 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For ANKRD27 (Source: Uniprot.org, NCBI)
Gene Name
ANKRD27
Full Name
Ankyrin repeat domain-containing protein 27
Weight
116.984kDa
Alternative Names
ankyrin repeat domain 27 (VPS9 domain); ankyrin repeat domain-containing protein 27; DKFZp434L0718; FLJ00040; VARP; Vps9 domain and ankyrin-repeat-containing protein; VPS9 domain-containing protein; VPS9-ankyrin-repeat protein ANKRD27 PP12899, VARP ankyrin repeat domain 27 ankyrin repeat domain-containing protein 27|VPS9 domain-containing protein|VPS9-ankyrin-repeat protein|Vps9 domain and ankyrin-repeat-containing protein|ankyrin repeat domain 27 (VPS9 domain)
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ANKRD27, check out the ANKRD27 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ANKRD27: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-VARP ANKRD27 Antibody (A08157)
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No publications found for A08157
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