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- Table of Contents
CDH5 antibody (PA2079) performs well in IHC, ICC, WB and shows reactivity with Human, Mouse, Rat.
- Validated for inter-lot consistency, specificity, and reproducibility
- Committed to quality since 1993
- Over 11 Publications
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Anti-VE Cadherin antibody, PA2079, IHC(P)
IHC(P): Rat Brain Tissue
IHC(P): Rat Brain Tissue
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Anti-VE-Cadherin CDH5-Antibody Picoband®
CDH5 antibody
| Reactive Species | Host | Application |
|---|---|---|
| Human, Mouse, Rat | Rabbit | IHC, ICC, WB |
Tested Applications
CDH5 antibody was positively detected by WB in:
A549 Whole Cell, HELA Whole Cell, MCF-7 Whole Cell, SK-HEP1 Whole cell
Suggested blocking solution with 5% non-fat milk or BSA; (*)Recommended protein loading: 20-40 ug per lane
CDH5 antibody was positively detected by IHC in:
Human Lung Cancer Tissue, Rat Brain Tissue
Use TE buffer pH 9.0 for antigen retrieval; (*) citrate buffer pH 6.0 is an alternative.
CDH5 antibody was positively detected by ICC/IF in:
human SK-HEP1 cells
Recommend Dilution
Application
Dilution
Species
Western blot
0.1-0.5μg/ml
Human
Immunohistochemistry (Paraffin-embedded Section)
2-5μg/ml
Human, Mouse, Rat
* It is recommended to optimize the amount of this reagent in each experimental system to achieve the best results.
Reactive Data
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IHC
ICC
IF
Human
Tested
Tested
Tested
Rat
Tested
Recommend
Monkey
Predicted
Predicted
Predicted
Product Information
Product Name
Anti-VE-Cadherin CDH5-Antibody Picoband®
View all CDH5 Antibodies
View all CDH5 Antibodies
Form
Lyophilized
Uniprot
Gene ID
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Host
Rabbit
Contents
Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human VE Cadherin, different from the related mouse and rat sequences by three amino acids.
Cross-Reactivity
No cross-reactivity with other proteins
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Observed Molecular Weight
130 kDa
Calculated Molecular Weight
87.5 kDa
Background of CDH5
CDH5 (Cadherin 5), also known as VE-cadherin, is a type of cadherin. It is encoded by the human gene CDH5. Kremmidiotis et al. (1998) mapped the human CDH5 gene to 16q22.1 using somatic cell hybrid panels. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. Therefore it was concluded that VE-cadherin serves the purpose of maintaining newly formed vessels.
Cite This Product
Anti-VE-Cadherin CDH5-Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA2079)
Antibody Homology Across Species
The results generated by this homology analysis tool for commonly used animal species are shown below. For unlisted species, please refer to the homology analysis between the immunogen sequence and the corresponding species.
A homology of ≥90% is recommended. Generally, higher homology indicates a greater potential for cross-species reactivity. However, protein expression levels may vary among different species, tissues, and cell types. Therefore, the homology analysis results are for reference only and do not guarantee antibody cross-reactivity or experimental performance.
Human
100%
High Homology
Monkey
100%
High Homology
Cow
89%
Moderate Homology
Sheep
89%
Moderate Homology
Mouse
84%
Moderate Homology
Rat
84%
Moderate Homology
Dog
68%
Low homology
Zebrafish
47%
Low homology
Rabbit
42%
Low homology
Homology ≥ 90%High Homology
70% ≤ Homology < 90%Moderate Homology
Homology < 70%Low homology
Protocols
Western Blot protocol for CDH5 antibody
Immunohistochemistry (IHC) protocol for CDH5 antibody
Immunocytochemistry/Immunofluorescence (ICC/IF) protocol for CDH5 antibody
Publications
Application:
Species:
Ulinastatin attenuates capillary leakage and suppresses FoxO1-dependent angiopoietin-2 in sepsis-associated acute lung injury via PI3K pathway
Published: 2026-04-28
Journal: PLoS One
Application: WB,IHC
Impact Factor: 2.60
Species: Rat,Human
PMID: 42048334
Thymoquinone alleviates the accumulation of ROS and pyroptosis and promotes perforator skin flap survival through SIRT1/NF-κB pathway
Published: 2025-03-25
Journal: Frontiers in Pharmacology
Application: WB
Impact Factor: 4.80
Species: Rat
PMID: 40201684
Exosomes derived from adipose tissue-derived stem cells alleviated H2O2-induced oxidative stress and endothelial-to-mesenchymal transition in human umbilical vein endothelial cells by inhibition of the mir-486-3p/Sirt6/Smad signaling pathway
Published: 2024-05-25
Journal: CELL BIOLOGY AND TOXICOLOGY
Application: WB,IF
Impact Factor: 5.30
Species: Mouse,Human
PMID: 38789630
Celastrol enhances the viability of random-pattern skin flaps by regulating autophagy through the AMPK-mTOR-TFEB axis
Published: 2024-04-10
Journal: PHYTOTHERAPY RESEARCH
Application: IHC,WB
Impact Factor: 6.10
Species: Rat
PMID: 38600729
Regorafenib inhibits migration, invasion, and vasculogenic mimicry of hepatocellular carcinoma via targeting ID1-mediated EMT
Published: 2021-01-11
Journal: MOLECULAR CARCINOGENESIS
Application: WB
Impact Factor: 4.78
Species: Human
PMID: 33428809
Gastrodin Promotes the Survival of Random-Pattern Skin Flaps via Autophagy Flux Stimulation
Published: 2021-01-09
Journal: Oxidative Medicine and Cellular Longevity
Application: WB,IHC
Impact Factor: 6.54
Species: Rat
PMID: 33505583
Effect of MicroRNA-126a-3p on Bone Marrow Mesenchymal Stem Cells Repairing Blood-brain Barrier and Nerve Injury after Intracerebral Hemorrhage
Published: 2020-03-09
Journal: Journal of Stroke & Cerebrovascular Diseases
Application: ICC
Impact Factor: 1.79
Species: Rat
PMID: 32160957
miR-181b-5p inhibits endothelial-mesenchymal transition in monocrotaline-induced pulmonary arterial hypertension by targeting endocan and TGFBR1
Published: 2019-11-14
Journal: TOXICOLOGY AND APPLIED PHARMACOLOGY
Impact Factor: 3.59
PMID: 31734320
Valproic acid enhances the viability of random pattern skin flaps: involvement of enhancing angiogenesis and inhibiting oxidative stress and apoptosis
Published: 2018-11-16
Journal: Drug Design Development and Therapy
Application: IHC
Impact Factor: 2.94
Species: Rat
PMID: 30510403
Exposure to Concentrated Ambient Fine Particulate Matter Induces Vascular Endothelial Dysfunction via miR-21
Published: 2017-07-06
Journal: International Journal of Biological Sciences
Application: WB,IHC
Impact Factor: 3.87
Species: Rat,Human
PMID: 28808419
Protein tyrosine phosphatase receptor U (PTPRU) is required for glioma growth and motility
Published: 2014-05-29
Journal: CARCINOGENESIS
Application: WB
Impact Factor: 5.27
Species: Human,Rat
PMID: 24876153
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Product Promise
We promise Anti-VE-Cadherin CDH5-Antibody Picoband® performs excellently in relevant applications for IHC, ICC, WB. If it doesn't perform as promised, we will refund the product. Learn more
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PA2079
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00
Troubleshooting
Boster Guarantee
Guaranteed product quality
We promise all of our products perform as described in datasheets.
This product is for Research Use Only. Not for use in diagnostic procedures.
Update date:
Oct 7, 2026