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Product Info Summary
| SKU: | A10601 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IHC-P, WB |
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Product info
Product Name
Anti-VNN3 Antibody
SKU/Catalog Number
A10601
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-VNN3 Antibody (Catalog # A10601). Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
VNN3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-VNN3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A10601)
Host
Rabbit
Contents
VNN3 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
VNN3 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human VNN3. The immunogen is located within the last 50 amino acids of VNN3.
Cross-reactivity
Multiple isoforms of VNN3 are known to exist.
Reactive Species
A10601 is reactive to VNN3 in Human, Mouse, Rat
Observed Molecular Weight
68 kDa
Calculated molecular weight
56.1 kDa
Background of VNN3
The vanin family is a novel group of ectoenzymes that function in tissue repair and plays a role in oxidative-stress response. As both secreted and membrane proteins, the vanin family members have been implicated as therapeutic targets in inflammatory disease. VNN3 (vascular non-inflammatory molecule 3), also known as Vanin3, is a 501 amino acid GPI-anchored amidohydrolase that is widely expressed and is found at highest levels in blood and liver. Induced by Th17 / Th1 type cytokines, VNN3 converts pantetheine into pantothenic acid. Containing one CN hydrolase domain, VNN3 is encoded by a gene that maps to human chromosome 6q23.2.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A10601 is guaranteed for ELISA, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
VNN3 antibody can be used for detection of VNN3 by Western blot at 0.5 and 1 μg/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of VNN3 in human brain tissue lysate with VNN3 antibody at (A) 0.5 and (B) 1 μg/mL.
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Immunohistochemistry of VNN3 in human liver tissue with VNN3 antibody at 5 μg/mL.
Specific Publications For Anti-VNN3 Antibody (A10601)
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