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Product Info Summary
| SKU: | A05575 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | IF, WB |
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Product info
Product Name
Anti-VPS11 Antibody
SKU/Catalog Number
A05575
Size
100ul
Form
Liquid
Description
Boster Bio Anti-VPS11 Antibody catalog # A05575. Tested in WB,IF applications. This antibody reacts with Human,Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-VPS11 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05575)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human LSM1 protein.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A05575 is reactive to VPS11 in Human, Mouse
Applications
A05575 is guaranteed for IF, WB Boster Guarantee
Observed Molecular Weight
111 kDa
Calculated molecular weight
107.837kDa
Background of VPS11
Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe3+ to Fe2+. Can also reduce of Cu2+ to Cu1+, suggesting that it participates in copper homeostasis. Uses NADP+ as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.
Passer B.J., Proc. Natl. Acad. Sci. U.S.A. 100:2284-2289(2003).
Korkmaz C.G., Oncogene 24:4934-4945(2005).
Steiner M.S., Cancer Res. 60:4419-4425(2000).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
IF: 1:50-1:200
Validation Images & Assay Conditions
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Figure 1. Western blotting validation for Anti-VPS11 Antibody A05575
Western blot analysis of extracts of mouse pancreasProtein Target Info & Infographic
Gene/Protein Information For VPS11 (Source: Uniprot.org, NCBI)
Gene Name
VPS11
Full Name
Vacuolar protein sorting-associated protein 11 homolog
Weight
107.837kDa
Superfamily
VPS11 family
Alternative Names
hVPS11; PEP5; RING finger protein 108; RNF108END1; vacuolar protein sorting 11 (yeast homolog); vacuolar protein sorting 11 homolog (S. cerevisiae); vacuolar protein sorting protein 11; vacuolar protein sorting-associated protein 11 homolog VPS11 END1, HLD12, PEP5, RNF108, hVPS11 VPS11 core subunit of CORVET and HOPS complexes vacuolar protein sorting-associated protein 11 homolog|RING finger protein 108|VPS11, CORVET/HOPS core subunit|vacuolar protein sorting 11 homolog
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on VPS11, check out the VPS11 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for VPS11: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-VPS11 Antibody (A05575)
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No publications found for A05575
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