Anti-WWP2 Antibody

Product Name

Anti-WWP2 Antibody

View all WWP2 Antibodies

SKU/Catalog Number

A03634

Size

100ul

Form

Liquid

Description

Boster Bio Anti-WWP2 Antibody catalog # A03634. Tested in WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-WWP2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03634)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human BLNK around the phosphorylation site of Y96.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A03634 is reactive to WWP2 in Human

Applications

A03634 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

98.912kDa

Background of WWP2

Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis By similarity. Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling (in vitro).

Benovic J.L., J. Biol. Chem. 268:19521-19527(1993).
Haribabu B., Proc. Natl. Acad. Sci. U.S.A. 90:9398-9402(1993).
Stoffel R.H., J. Biol. Chem. 269:27791-27794(1994).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:2000

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

Gene/Protein Information For WWP2 (Source: Uniprot.org, NCBI)

Alternative Names

AIP2Nedd-4-like ubiquitin-protein ligase; atrophin-1 interacting protein 2; Atrophin-1-interacting protein 2; EC 6.3.2; EC 6.3.2.-; NEDD4-like E3 ubiquitin-protein ligase WWP2; WW domain containing E3 ubiquitin protein ligase 2; WW domain-containing protein 2; WWp2-like WWP2 AIP2, WWp2-like WW domain containing E3 ubiquitin protein ligase 2 NEDD4-like E3 ubiquitin-protein ligase WWP2|HECT-type E3 ubiquitin transferase WWP2|atrophin-1 interacting protein 2

For more info on WWP2, check out the WWP2 Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for WWP2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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