Anti-ZIP2 SLC39A2 Antibody

Product Name

Anti-ZIP2 SLC39A2 Antibody

View all SLC39A2 Antibodies

SKU/Catalog Number

A09140-1

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-ZIP2 SLC39A2 Antibody (Catalog # A09140-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

ZIP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-ZIP2 SLC39A2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09140-1)

Host

Rabbit

Contents

ZIP2 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

ZIP2 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human ZIP2. The immunogen is located within amino acids 70 - 120 of ZIP2.

Reactive Species

A09140-1 is reactive to SLC39A2 in Human, Mouse, Rat

Observed Molecular Weight

68 kDa

Calculated molecular weight

32.7 kDa

Background of SLC39A2

The zinc transporter ZIP2, also known as SLC39A2, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. Similar to knock-outs of ZIP1 and ZIP3, ZIP2-null mice have no phenotypic differences compared to wild-type mice. Only when ZIP1, ZIP2, and ZIP3 genes are all eliminated and these mutant mice are fed a zinc-deficient diet do abnormalities such as reduced embryonic-membrane bound alkaline phosphatase activity and abnormal development occur, indicating that the ZIP1-3 proteins play an important, noncompensatory role when zinc is deficient. More recent studies have shown that ZIP2 and ZIP3 are down regulated in human prostate adenocarcinomatous glands, and may be important in the retention of zinc in the cellular compartment.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A09140-1 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

ZIP2 antibody can be used for detection of ZIP2 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse and rat samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

See full target information SLC39A2

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