A3GALT2 Antibodies

AND A3GALT2 ELISA kits, A3GALT2 Proteins

Many biological assays use antibodies to detect A3GALT2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with A3GALT2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop A3GALT2 antibodies...

We validate the specificity of these antibodies to A3GALT2 by testing them on tissues known to express A3GALT2 positively and negatively. Browse below to find the A3GALT2 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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A3GALT2 Infographic by Boster Bio

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A3GALT2 Overview

Facts about Alpha-1,3-galactosyltransferase 2.

A3GALT2 3D structure. Source: alphafold

Alpha-1,3-galactosyltransferase 2 (A3GALT2)

Synthesizes the galactose-alpha(1,3)-galactose group on the glycosphingolipid isoglobotrihexosylceramide or isogloboside 3 (iGb3) by catalyzing the transfer of galactose from UDP-Galactose to its acceptor molecule Gal-beta-1,4-Glc-ceramide. Can also catalyze the addition of galactose to iGb3 itself to form polygalactose structures.

Gene Information

Human
Gene Name:	A3GALT2
Uniprot:	U3KPV4
Entrez:	127550

Family

Belongs to:

glycosyltransferase 6 family

Alternative Names

Alpha-1,3-galactosyltransferase 2

Molecular Weight

Mass (kDA):
38.754 kDA

Genomic Context


Human

Location:	1p35.1
Sequence:	1; NC_000001.11 (33306766..33321098, complement)

Tissue Specificity

Expressed in thymus and monocyte derived dendritic cells.

Subcellular Localizations

Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Also found in numerous large vesicles throughout the cytoplasm of the soma.

PTMs

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/A3GALT2

References

PMID: 18630988 by Christiansen D., et al. Humans lack iGb3 due to the absence of functional iGb3-synthase: implications for NKT cell development and transplantation.

PMID: 23378701 by Tahiri F., et al. Lack of iGb3 and isoglobo-Series glycosphingolipids in pig organs used for xenotransplantation: implications for natural killer T-cell biology.