ABCC12 Antibodies

Multidrug resistance-associated protein 9 (ABCC12)

Probable transporter. .

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Gene Information

Human
Gene Name:	ABCC12
Uniprot:	Q96J65
Entrez:	94160

Family

Belongs to:
ABC transporter superfamily

Alternative Names

ATP-binding cassette transporter sub-family C member 12; ATP-binding cassette, sub-family C (CFTR/MRP), member 12; MGC27071; MRP9ATP-binding cassette sub-family C member 12; multidrug resistance-associated protein 9

Molecular Weight

Mass (kDA):
152.297 kDA

Genomic Context

Human
Location:	16q12.1
Sequence:	16; NC_000016.10 (48082973..48146770, complement)

Tissue Specificity

Expressed in testis (at protein level). Widely expressed at low level. Isoform 5 is specifically expressed in brain, testis and breast cancer cells.

Subcellular Localizations

Membrane; Multi-pass membrane protein.

Diseases

• Cystic Fibrosis
• Fibrosis
• Neoplasms
• Malignant Neoplasms
• Myeloproliferative Syndrome, Transient
• Jaundice, Chronic Idiopathic
• Hereditary Diseases
• Hypoglycemia Of Infancy
• Liver Carcinoma
• Malignant Neoplasm Of Breast
• Nesidioblastosis
• Degenerative Polyarthritis
• Carcinoma

• Arthritis
• Arthropathy
• Genetic Diseases, Inborn
• Liver Neoplasms
• Inflammation
• Mammary Neoplasms
• Rheumatoid Arthritis

Pathways

• Transport
• Drug Resistance
• Gene Silencing
• Drug Transport
• Posttranscriptional Gene Silencing
• Regulation Of Gene Expression

• Localization

PTMs

• Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ABCC12

ABCC12 Marker Review

You have found the right place if you are looking for a review of the ABCC12 marker. The information here covers the ABCC12 Marker, the Anti-ABCC12 Marker, and Boster Bio: Best Uses of The ABCC12 Marker. It also covers gene infographics and the benefits of ABCC12Marker. This article covers Boster Bio's Best Uses of the ABCC12 Marker in Gene Infographics

ABCC12 Marker

The ABCC12 genetic member is a member in the ABCB11 superfamily. It is expressed primarily in the liver and is a candidate marker for hepatocellular carcinoma. The development of hepatitis C is also associated to this gene. This is a type if liver cancer that affects young children. Although it cannot predict the onset of hepatocellular cancer, this marker can improve the prognosis and survival rates of children who have been affected by the mutation.

Benefits from using the ABCC12Marker

The ABCC12 gene may be a biomarker for breast carcinoma. Studies have shown that ABCC gene expression is linked to the presence of ER and PR. This marker could be useful in guiding treatment. The ABCC genes is a carrier of lipids. It also contains amino acids, steroids, and chemical substances, including chemotherapy drugs. High ABCC gene expression is associated with resistance to chemotherapy. Understanding the role of the ABCC gene in BC can help improve treatment options for patients.